Correlation of Thallium Uptake With Left Ventricular Wall Thickness by Cine Magnetic Resonance Imaging in Patients With Acute and Healed Myocardial Infarcts

Lawson, Mark A.; Johnson, Lynne L.; Coghlan, Leslie; Alami, Mohamed; Tauxe, E. Lindsey; Reinert, Steven E.; Singleton, Ross R.; Pohost, Gerald M.

doi:10.1016/s0002-9149(97)00391-3

Cited by 31 publications

(12 citation statements)

References 15 publications

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“…Clinical studies have shown that preserved wall thickness and systolic wall thickening measured with MRI are indicative of residual viability [75][76][77][78]. MRI findings have been validated using 201 Tl-SPECT and 18 F-FDG PET [107][108][109].…”

Section: Cardiac Functionmentioning

confidence: 98%

Usefulness of Magnetic Resonance Imaging in Cardiac and Enovascular Intervention

Saeed¹

2006

CMIR

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Assessment of ischemic heart disease is an important application of magnetic resonance imaging (MRI). This noninvasive diagnostic technique has the potential to evaluate different aspects of ischemic heart disease such as myocardial function, perfusion and the extent of acute and chronic infarctions. MRI is becoming an alternative technique for assessment of myocardial viability by predicting systolic recovery of stunned and hibernating myocardium after revascularization. MR contrast agents provide additional information on residual myocardial viability, myocardial perfusion, coronary angiography and microvascular integrity. Recent technologic improvements in scanners, sequences and post-processing of images showed the potentiality of MR-guided procedures. This review begins with a brief overview of magnetic resonance properties and MR contrast agents and proceeds to their applications in cardiac imaging and endovascular intervention. The next generation of MR contrast agents will likely focus on increase detection sensitivity so that minor tissue changes can be detected, prolonging intravascular retention (blood pool contrast agents), improving tissue targeting (tissue and molecule specific contrast agents and probes) and molecular imaging. MRI will play viable role in cardiovascular imaging and intervention in the near future and it may have the potential to complement other commonly used diagnostic modalities.

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Section: Cardiac Functionmentioning

confidence: 98%

Usefulness of Magnetic Resonance Imaging in Cardiac and Enovascular Intervention

Saeed¹

2006

CMIR

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“…A resting LV end-diastolic wall thickness of less than 5.5 mm has been associated with segments that do not display contractile reserve and exhibit histologic evidence of transmural scar [35]. Several months after infarction, an end-systolic wall thickness of greater than 8.5 mm has been found associated with a thallium uptake of greater than 50% and residual viability [36]. Baer et al [37] have compared dobutamine transesophageal echocardiogram and DMRI for detecting myocardial viability.…”

Section: Detection Of Viabilitymentioning

confidence: 99%

Magnetic resonance imaging assessment of cardiac function

Hundley

Hamilton²,

Rerkpattanapipat³

2003

Curr Cardiol Rep

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Measurements of left ventricular function at rest and during stress are useful for identifying myocardial ischemia, injury, and the risk of subsequent myocardial infarction. Without ionizing radiation or intravascular contrast administration, magnetic resonance imaging techniques can be used to acquire precise measurements of left ventricular function. This relatively new development may enhance a physician's ability to provide care to patients with cardiovascular disease.

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“…Baer et al [4] used wall thickness and thickening criteria by cine MRI to define viable myocardium and scar and used these definitions to understand the physiologic information portrayed by 99m Tc sestamibi SPECT. Lawson et al [53] compared wall thickness by cine MRI to 201 Tl SPECT and concluded that end-systolic wall thickness by MRI is the best non-invasive parameter of myocardial scar. The data of these and other published reports suggest that myocardial regions with preserved wall thickness and thickening by cine MRI should be interpreted as viable whereas thinned, akinetic regions should be interpreted as non-viable.…”

Section: Wall Thickness and Thickeningmentioning

confidence: 99%

Evaluation of Myocardial Viability by MRI

Kim

Hillenbrand

Judd

2000

Herz

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Distinguishing between viable and non-viable myocardium is an important clinical issue. Several magnetic resonance (MR) techniques to address this issue have been proposed. Spectroscopy of phosphorus-31 and hydrogen-1 from creatine as well as imaging of sodium-23 and potassium-39 reflect information related to cellular metabolism. The spatial and temporal resolutions of these techniques are limited, however, by the small magnitude of the MR signal. Proton imaging techniques include examination of pathologic alterations in MR relaxation times (T1 and T2), wall thickness and thickening, cine MRI combined with low-dose dobutamine, first-pass contrast enhancement patterns, and delayed contrast enhancement patterns. Of the proton imaging approaches, cine MRI combined with low-dose dobutamine is supported by the largest body of clinical evidence supporting the hypothesis that the technique yields useful information regarding myocardial viability. Recent data suggest that delayed contrast enhancement examines the transmural extent of viable myocardium irrespective of contractile function and that this technique should also be considered in a clinical setting.

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Correlation of Thallium Uptake With Left Ventricular Wall Thickness by Cine Magnetic Resonance Imaging in Patients With Acute and Healed Myocardial Infarcts

Cited by 31 publications

References 15 publications

Usefulness of Magnetic Resonance Imaging in Cardiac and Enovascular Intervention

Usefulness of Magnetic Resonance Imaging in Cardiac and Enovascular Intervention

Magnetic resonance imaging assessment of cardiac function

Evaluation of Myocardial Viability by MRI

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