Correlation of the clinical severity of atopic dermatitis with ocular comorbidities

Numata, Takafumi; Ito, Toshifumi; Yamamoto, Kaori; Kawakami, Setsuko; Wakabayashi, Yoshihiro; Gotô, Hiroshi; Tsuboi, Ryoji; Okubo, Yukari

doi:10.1002/cia2.12127

Cited by 1 publication

(3 citation statements)

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“…Head and neck score in AD patients presenting with lens opacity and retinal lesions is higher than that of AD patients without ocular complication; however, the difference was not statistically significant. 33 In this study, the total number of subjects was 70, and the prevalence of each ocular complication was different from our study. Therefore, the result can be different from our study due to statistical difference.…”

Section: Discussioncontrasting

confidence: 56%

“…However, in our study, no significant associations were found between intraocular complications such as cataract, retinal break, and retinal detachment and the total score for AD severity. In a study by Takafumi et al., 33 a significant association was observed between blepharitis and the whole body EASI score, but this association was not observed with the head and neck EASI score in Japanese patients. Head and neck score in AD patients presenting with lens opacity and retinal lesions is higher than that of AD patients without ocular complication; however, the difference was not statistically significant 33 .…”

Section: Discussionmentioning

confidence: 85%

“…In a study by Takafumi et al., 33 a significant association was observed between blepharitis and the whole body EASI score, but this association was not observed with the head and neck EASI score in Japanese patients. Head and neck score in AD patients presenting with lens opacity and retinal lesions is higher than that of AD patients without ocular complication; however, the difference was not statistically significant 33 . In this study, the total number of subjects was 70, and the prevalence of each ocular complication was different from our study.…”

Section: Discussionmentioning

confidence: 85%

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Comprehensive evaluation of ocular complications in atopic dermatitis: insights from a contemporary cohort study in Korean population

Seo,

Han,

Kim

et al. 2023

Int J Dermatology

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BackgroundAtopic dermatitis (AD) is a chronic inflammatory skin disorder associated with various systemic and ocular complications. This study aimed to investigate the prevalence, risk factors, and clinical characteristics of ocular complications in a cohort of Korean AD patients.MethodsA retrospective review of medical records was conducted for AD patients who visited the dermatology and ophthalmology clinics at the same institution. Demographic data, clinical characteristics, and types of ocular complications were recorded. Logistic regression analysis was performed to identify factors associated with ocular complications.ResultsA total of 212 AD patients were included in the study. The intraocular complications had a prevalence of 1.9%, whereas ocular surface diseases were observed more frequently, with prevalence of 13.2%. Among the ocular complications, blepharitis was the most prevalent, followed by atopic keratoconjunctivitis. Subcapsular cataract, atrophic hole, and retinal detachment were also observed. The head and neck score in the Eczema Area and Severity Index (EASI) emerged as a significant predictor for intraocular complications, independent of age, gender, total EASI score, and family history. No significant association was found between total EASI score and ocular surface disease.ConclusionThis study provides insights into the prevalence and risk factors of ocular complications in Korean AD patients. The head and neck score in EASI was identified as a significant predictor for intraocular complications. These findings emphasize the importance of comprehensive evaluation and interdisciplinary care for AD patients, particularly in identifying and managing potential vision‐threatening complications.

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Section: Discussioncontrasting

confidence: 56%

Section: Discussionmentioning

confidence: 85%