2020
DOI: 10.21203/rs.3.rs-41582/v2
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Correlation study between Interleukin-17 Gene Polymorphisms and risk of development of recurrent aphthous ulcer in Han Chinese Population

Abstract: ObjectiveInterleukin-17 (IL-17) is a pleiotropic cytokine which plays important role in the inflammatory diseases.MethodsPolymorphisms of IL-17A rs2275913 and IL17F rs763780 were measured in 125 RAU cases and 116 healthy controls. The polymerase chain reaction-restriction fragment length was measured. The genotype distribution and disease risk, and its’ relationship with RAU severity was analyzed.ResultsRAU risk were related with polymorphism of IL-17 gene at rs2275913 site after adjusting BMI, sex, age, smoki… Show more

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