The category of personality is one of the basic concepts for psychology, but at the same time the most controversial in theoretical and methodological terms. That is why the study of personal characteristics in different populations, ethnicities, ages, professional groups, etc. still does not lose its relevance in the scientific field. Given that certain components of individual personality traits are innate, it is advisable to find connections between them and the characteristics of the human body. The purpose of the work is to determine and analyze the peculiarities of correlations between indicators of body structure and size and personality indicators of practically healthy women with mesomorphic somatotype. Primary anthropo-somatotypological and personality indicators of 33 practically healthy Ukrainian women of the first mature age of mesomorphic somatotype were selected from the data bank of materials of the research center of National Pirogov Memorial Medical University, Vinnytsya. The analysis of correlations between anthropo-somatotypological and indicators of personality traits was performed in the licensed package "Statistica 6.1" using the non-parametric Spearman's method. Multiple, mostly reliable, medium-strength straight lines (r = -0.35 to -0.50), Eysenck G. insincerity scales with the majority of girth dimensions, thickness of skin and fat folds, somatotype components, and body weight component composition; multiple, mostly significant medium-strength inverse (r = -0.37 to -0.52) correlations of the exaltation character of the exalted type according to Shmishek G. with the majority of girth dimensions, the majority of pelvic sizes, somatotype components and components of body weight composition; multiple significant mean strength inverse (r = -0.38 to -0.49) correlations of the extraversion-introversion scale according to Eysenck G. with the thickness of the skin and fat folds of the upper limb and under the shoulder blade. In other cases, single, medium-strength, reliable and unreliable direct and inverse correlations of anthropo-somatotypological indicators with the leading typological characteristics of temperament, psychodynamic features of personality and indicators of severity and features of accentuated personality traits. As a result of quantitative analysis of reliable and unreliable average correlations of anthropo-somatotypological indicators with personality traits of practically healthy women of mesomorphic somatotype, the highest relative percentage of correlations was found between: leading typological characteristics of temperament according to Eysenck G. and somatotype components body weight composition and body girth; psychodynamic personality traits according to Spielberger C. D. and longitudinal body size, thickness of skin and fat folds and components of the somatotype; indicators of severity and features of accentuated personality traits according to Shmishek G. and indicators of the component composition of body weight, somatotype components, body circumference and thickness of skin and fat folds; indicators of the level of subjective control over Rotter J. and the width of the distal epiphyses of the extremities and the transverse dimensions of the body.