Correlations of C-reactive protein levels with anthropometric profile, percentage of body fat and lipids in healthy adolescents and young adults in urban North India

Vikram, Naval Kishore; Misra, Anoop; Dwivedi, Manjari; Sharma, Rekha; Pandey, Ravindra Mohan; Luthra, Kalpana; Chatterjee, Ananya; Dhingra, Vibha; Jailkhani, B. L.; Kk, Talwar; Guleria, Randeep

doi:10.1016/s0021-9150(03)00096-0

Cited by 118 publications

(103 citation statements)

References 34 publications

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“…Two studies were conducted in New Delhi by our group (AM, NKV): the first on urban adult population 12 and the second on subjects aged 14-25 years. 13 The first study from New Delhi included subjects residing in an urban resettlement colony. Out of the total population of about 30 000, 650 subjects were screened using systematic random sampling method.…”

Section: Study Design and Sampling Methodsmentioning

confidence: 99%

“…The second study from New Delhi included subjects aged 18-25 years drawn from an approximate total population of 15 000 subjects from schools and colleges of southwest Delhi using multistage cluster sampling based on modified World Health Organization (WHO) Expanded Program of Immunization Sampling Plan as described elsewhere. 13 Complete data were available for 512 subjects in this age group, which were used for analysis in this study. The third study, Jaipur Heart Watch-2 (JHW-2), was conducted by another investigator (RG) in the city of Jaipur located in the northwest of Rajasthan, nearly 250 km from New Delhi, according to the previously published methods.…”

Section: Study Design and Sampling Methodsmentioning

confidence: 99%

“…13,16,17 Total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-c) were measured according to the methods described earlier 13,16,17 Low-density lipoprotein cholesterol (LDL-c) levels were calculated using the Friedewald's formula. 18 Definitions Value of BMI X23 kg/m 2 was used to define overweight and X25 kg/m 2 was used to define obese.…”

Section: Biochemical Measurementsmentioning

confidence: 99%

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Waist circumference cutoff points and action levels for Asian Indians for identification of abdominal obesity

et al. 2005

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Objective: To test the validity of internationally accepted waist circumference (WC) action levels for adult Asian Indians. Design: Analysis of data from multisite cross-sectional epidemiological studies in north India. Subjects: In all, 2050 adult subjects 418 years of age (883 male and 1167 female subjects). Measurements: Body mass index (BMI), WC, waist-to-hip circumference ratio, blood pressure, and fasting samples for blood glucose, total cholesterol, serum triglycerides, and high-density lipoprotein cholesterol. Results: In male subjects, a WC cutoff point of 78 cm (sensitivity 74.3%, specificity 68.0%), and in female subjects, a cutoff point of 72 cm (sensitivity 68.7%, specificity 71.8%) were appropriate in identifying those with at least one cardiovascular risk factor and for identifying those with a BMI 421 kg/m 2 . WC levels of X90 and X80 cm for men and women, respectively, identified high odds ratio for cardiovascular risk factor(s) and BMI level of X25 kg/m 2 . The current internationally accepted WC cutoff points (102 cm in men and 88 cm in women) showed lower sensitivity and lower correct classification as compared to the WC cutoff points generated in the present study. Conclusion: We propose the following WC action levels for adult Asian Indians: action level 1: men, X78 cm, women, X72 cm; and action level 2: men, X90 cm, women, X80 cm.

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Section: Study Design and Sampling Methodsmentioning

confidence: 99%

Section: Study Design and Sampling Methodsmentioning

confidence: 99%

Section: Biochemical Measurementsmentioning

confidence: 99%

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Waist circumference cutoff points and action levels for Asian Indians for identification of abdominal obesity

et al. 2005

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“…According to our recent data , the prevalence of overweight/obesity among adolescent children (14-17 years) belonging to high-and middle-income groups in Delhi was 29% (Bhardwaj et al, 2008). Increased generalized and central obesity showed association with subclinical inflammation, atherogenic dyslipidemia (Vikram et al, 2003) and insulin resistance in these adolescents, making them at risk for metabolic syndrome and atherosclerosis during early adulthood. We have previously reported that childhood metabolic syndrome tracks into adulthood (Misra et al, 2007).…”

Section: Introductionmentioning

confidence: 93%

Effects of controlled school-based multi-component model of nutrition and lifestyle interventions on behavior modification, anthropometry and metabolic risk profile of urban Asian Indian adolescents in North India

et al. 2010

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Background/Objectives: To study the effectiveness of a multi-component intervention model of nutrition and lifestyle education on behavior modification, anthropometry and metabolic risk profile of urban Asian-Indian adolescents in North India. Subjects/Methods: Two schools matched for student strength and middle socioeconomic strata were randomly allocated to intervention and control group. Changes in nutrition-related knowledge, attitude, lifestyle practices, food frequency and body image of eleventh-grade students (15-17 years) in both schools were tested using a validated questionnaire. Anthropometric and biochemical measurements were made using standard methods. Segmental body composition analysis was carried out using an 8-electrode multifrequency bioelectrical impedance method of body fat estimation. Results: At 6 months follow-up, significant improvement in several domains of knowledge was observed in intervention children (n ¼ 99; males ¼ 60; females ¼ 39) as compared with control school children (n ¼ 102; males ¼ 61; females ¼ 41). In the intervention group, significantly lower proportion of children consumed aerated drinks (15.1%; Po0.001) and energy-dense unhealthy foods (8.9%; P ¼ 0.03), whereas significantly higher proportion brought tiffin (packed lunch) to school (14.9%; P ¼ 0.004) and brought a fruit in their tiffin (30.7%; Po0.001) as compared with the control group. Significant decrease in mean waist circumference (P ¼ 0.02, 95% confidence interval (CI) ¼ À2.43,À0.17), sagittal abdominal diameter (Po0.001, 95% CI ¼ À0.82,À0.09), waist-to-hip ratio (P ¼ 0.02, 95% CI ¼ À0.03,À0.004) and fasting blood glucose (P ¼ 0.05, 95% CI ¼ À0.09, 5.00) was seen in intervention as compared with control school children. Conclusions: Multi-component model of nutrition and lifestyle education was successful in improving the nutrition-related knowledge, eating habits and lifestyle practices, and resulted in beneficial changes in anthropometric and biochemical profiles of the Asian Indian adolescents. This model should be applied on countrywide basis to prevent obesity and diabetes.

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“…The accumulation of visceral (intra-abdominal or centrally distributed) adipose tissue has been shown to be more detrimental, in relation to the metabolic abnormalities found in MetS, than total body fat (Pouliot et al 1992;Despres et al 1995;Despres, 1997). At the same extent of body fatness, elevated visceral adiposity is associated with increased insulin resistance, elevated plasma TAG, glucose, insulin and lower HDL-cholesterol (Pouliot et al 1992;Chandalia et al 1999;Raji et al 2001;Vikram et al 2003). The fact that these abnormalities are key components of the MetS adds weight to the evidence that MetS arises as a consequence of increased central adiposity.…”

Section: Asian-specific Definitions For Obesity and Adipositymentioning

confidence: 99%

CVD risk in South Asians: the importance of defining adiposity and influence of dietary polyunsaturated fat

Lovegrove

2007

Proc. Nutr. Soc.

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The prevalence of the metabolic syndrome (MetS), CVD and type 2 diabetes (T2D) is known to be higher in populations from the Indian subcontinent compared with the general UK population. While identification of this increased risk is crucial to allow for effective treatment, there is controversy over the applicability of diagnostic criteria, and particularly measures of adiposity in ethnic minorities. Diagnostic cut-offs for BMI and waist circumference have been largely derived from predominantly white Caucasian populations and, therefore, have been inappropriate and not transferable to Asian groups. Many Asian populations, particularly South Asians, have a higher total and central adiposity for a similar body weight compared with matched Caucasians and greater CVD risk associated with a lower BMI. Although the causes of CVD and T2D are multi-factorial, diet is thought to make a substantial contribution to the development of these diseases. Low dietary intakes and tissue levels of long-chain (LC) n-3 PUFA in South Asian populations have been linked to high-risk abnormalities in the MetS. Conversely, increasing the dietary intake of LC n-3 PUFA in South Asians has proved an effective strategy for correcting such abnormalities as dyslipidaemia in the MetS. Appropriate diagnostic criteria that include a modified definition of adiposity must be in place to facilitate the early detection and thus targeted treatment of increased risk in ethnic minorities.

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Correlations of C-reactive protein levels with anthropometric profile, percentage of body fat and lipids in healthy adolescents and young adults in urban North India

Cited by 118 publications

References 34 publications

Waist circumference cutoff points and action levels for Asian Indians for identification of abdominal obesity

Waist circumference cutoff points and action levels for Asian Indians for identification of abdominal obesity

Effects of controlled school-based multi-component model of nutrition and lifestyle interventions on behavior modification, anthropometry and metabolic risk profile of urban Asian Indian adolescents in North India

CVD risk in South Asians: the importance of defining adiposity and influence of dietary polyunsaturated fat

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