Correlative Interrelations of the Tumor Microenvironment and Relative Risk of Unfavourable Outcome of Endometrioid Adenocarcinoma of the Corpus Uteri

Abstract

Objective : to identify correlative interrelations among the parameters of the tumor microenvironment of endometrioid adenocarcinoma and relative risk of its prognosis. Material and methods. Immunohistochemic and morphometric studies were performed on the histological material of 60 patients. Results. Correlative interrelations were revealed among the studied parameters in groups with favorable and unfavorable outcomes. Relative risks for progression of endometrioid adenocarcinoma of the corpus uteri were determined. Conclusion. The revealed differences in the interrelations among morphological and immunohistochemical parameters in female patients with endometrioid adenocarcinoma of the corpus uteri of different survival potential reflect biological features of the tumorous growth and the disease progression.