“…Recent ~ tudie high] ight the importance of hi tory and phy. ical examination a predictors of lower extremity DVT and when combined with clinical ri k fact r , can guide appropriate u e of imaging in those who need it most whit t excluding patient for whom it is not rel vant' :!• 11 • Common clinical situations such a calf tenderne and chronic unilateral welling Un the absence of risk factor ) clinically evident cellulitis and lower limb joint pain were not a sociated with acute DVT in a large eriesr 21 • The use of the D-dimer blood test promises to be a useful screening tool due to its very high negative predictive value for thrombus. It ha been predicted that inappropriate lower limb imaging referrals could be reduced by 35% if D-dimer levels are norma]H>.…”