Corrigendum to “A click-ready pH-triggered phosphoramidate-based linker for controlled release of monomethyl auristatin E” [Tetrahedron Lett. Volume 61, Issue 41, 8 October 2020, 152398]

Stimuli-responsive delivery strategies for controllable gene editing in tumor therapeutics

“…Therefore, numerous efforts have been devoted to design the core chemical structure of pH-responsive polymers to acidic microenvironments. There are a lot of research studies by chemists on numerous structures sensitive to acidic conditions, including imines, 33,34 hydrazones, [35][36][37][38][39] oximes, [40][41][42] carboxylic esters, 43,44 b-thiopropionates, [45][46][47] acetals or ketals, [48][49][50] silyl ethers, [51][52][53] phosphoramidates, 54,55 and so on. Due to the protonation of tertiary amine groups at low pH, the polymers containing tertiary amine groups would have a pH-responsive transition from hydrophobic to hydrophilic.…”