Corrigendum to “Efficacy Comparison of Five Different Acupuncture Methods on Pain, Stiffness, and Function in Osteoarthritis of the Knee: A Network Meta-Analysis”

Li, Shaowei; Xie, Pingjin; Liang, Zhenghui; Huang, Wei-Han; Huang, Zhanhui; Ou, Jinming; Lin, Zhiyong; Chai, Shengting

doi:10.1155/2019/3713197

Cited by 1 publication

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“…23 Acupuncture has been evaluated for the treatment of conditions including acute and chronic pain, anxiety, and various neuropsychiatric disorders. [24][25][26][27] Rat-model and human studies have shown that acupuncture may improve cognitive deficits in Alzheimer's disease. 28,29 In functional MRI studies of healthy adults, acupuncture has been shown to stimulate areas of the brain associated with memory and cognition.…”

Section: Introductionmentioning

confidence: 99%

Acupuncture Treatment of Delirium in Older Adults Hospitalized in Internal Medicine Departments: An Open-Label Pragmatic Randomized-Controlled Trial

Levy

Gavrieli

Hefer

et al. 2021

J Geriatr Psychiatry Neurol

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Background: Acupuncture seems to improve cognitive function in experimental models and to reduce agitation in dementia. The addition of acupuncture to standard-of-care (SOC) may improve clinical outcomes related to delirium in hospitalized older adults. Methods: This pragmatic open-label randomized-controlled trial evaluated 81 older adults hospitalized in an internal medicine ward and diagnosed with delirium. Fifty were randomized to daily acupuncture combined with SOC and 31 to SOC only for up to 1 week. Delirium was diagnosed using Confusion Assessment Method (CAM) tool, and its severity was assessed by the long CAM-Severity (CAM-S) tool. The primary study outcome was delirium resolution evaluated as time-to-first delirium remission (over 7 days) and the number of days spent delirium-free. Results: Time-to-first delirium remission was shorter in the acupuncture arm as compared to the SOC only arm (p < 0.001). A multivariate Cox regression analysis showed a shorter time-to-first remission of delirium in the acupuncture arm as compared with SOC arm [Hazard Ratio 0.267 (95% CI 0.098-0.726, p = 0.010)]. In the 7 days of evaluation, a significantly higher number of delirium-free days was found in the acupuncture arm compared to the SOC arm (p < 0.001), and CAM-S sum from day 2 to day 7 of evaluation was significantly lower in the acupuncture group compared to the control group (p = 0.002). No adverse safety event was found in the acupuncture group. Conclusion: Acupuncture seems to be safe and effective in the treatment of delirium in older patients hospitalized in internal medicine departments.

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