Corrigendum to “Intercomparison of dose enhancement ratio and secondary electron spectra for gold nanoparticles irradiated by X-rays calculated using multiple Monte Carlo simulation codes” [Phys. Med. 69 (2020) 147–163]

Li, W.B.; Maria, Salvatore Di; Friedland, W.; Heide, B.; Klapproth, A.P.; Li, C.Y.; Beuve, M.; Rabus, Hans; Rudek, Benedikt; Schuemann, Jan; Villagrasa, C.

doi:10.1016/j.ejmp.2020.10.008

Cited by 14 publications

(16 citation statements)

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“…[8] One hypothesis for the enhanced cell killing is a local enhancement of the radiation dose within the target volume due to an increased emission of low-energy secondary electrons from the AuNPs. [10][11][12][13][14][15][16] The local dose enhancement near the AuNPs is generally assessed by Monte Carlo (MC) simulation, which is currently the most accurate method for radiation transport calculations. [12,17,18] While significant advances have been made with respect to the MC algorithms used to model radiation effects, particle transport simulations are still based on crude approximations.…”

Section: Doi: 101002/ppsc202200136mentioning

confidence: 99%

Deposition of Gold Nanoparticles on a Self‐Supporting Carbon Foil

Hepperle

Baek

Nettelbeck

et al. 2022

Part & Part Syst Charact

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Electron emission cross sections of gold nanoparticles (AuNPs) are important for assessing their radiosensitizing effects from ionizing radiation using Monte Carlo simulations. Measurements of these data require samples of sufficiently large area density, homogeneous nanoparticle distribution, and a mechanically stable sample holder to ensure a low background signal. While several methods exist for the deposition of nanoparticles, there is little information regarding the deposition of AuNPs in an aqueous solution onto a self‐supporting film. The aim of this is to find suitable preparation techniques for AuNP samples which fulfill the above requirements. AuNP samples are produced using different deposition techniques and a 50 nm‐thick carbon foil as the substrate. These samples are characterized with respect to the size and spatial distribution of AuNPs using a scanning electron microscope. The drop‐casting technique yields the best results, while those obtained with the spin‐coater technique are less reproducible regarding sample stability. The microdrop method is deemed unsuitable due to its tendency to form AuNP clusters. Measurements conducted with a synchrotron radiation source, as well as with protons and electrons, confirm the suitability of these samples for studying electron emission spectra of AuNPs for different radiation types.

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Section: Doi: 101002/ppsc202200136mentioning

confidence: 99%

Deposition of Gold Nanoparticles on a Self‐Supporting Carbon Foil

Hepperle

Baek

Nettelbeck

et al. 2022

Part & Part Syst Charact

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“…In the first analysis, the ISO Guide to the expression of uncertainty in measurements was employed (ISO 1995) to interpret the reported results as independent measurements and to derive an uncertainty estimate for the dose enhancement by gold nanoparticles, where the probability distribution function had to be assumed to be log-normal to account for the large spread of the results. Further analysis revealed that the large differences between the reported results could be traced back to conceptional misunderstanding and improper implementations of the exercise (Rabus et al 2019, Li et al 2020b.…”

Section: Micro-and Nanodosimetrymentioning

confidence: 94%

“…Furthermore, the TG also supports the efforts of the international Geant4-DNA collaboration to include cross-sections for materials other than liquid water in their database. Major activities at present concern a code intercomparison exercise for estimating uncertainties in micro-and nanodosimetric simulations (Villagrasa et al 2019) and a code intercomparison exercise held jointly with WG 7 'Internal Dosimetry' on the dose enhancement around gold nanoparticles (Rabus et al 2020, Li et al 2020a, 2020b.…”

Section: Micro-and Nanodosimetrymentioning

confidence: 99%

Quality assurance for the use of computational methods in dosimetry: activities of EURADOS Working Group 6 ‘Computational Dosimetry’

et al. 2021

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Working Group (WG) 6 ‘Computational Dosimetry’ of the European Radiation Dosimetry Group promotes good practice in the application of computational methods for radiation dosimetry in radiation protection and the medical use of ionising radiation. Its cross-sectional activities within the association cover a large range of current topics in radiation dosimetry, including more fundamental studies of radiation effects in complex systems. In addition, WG 6 also performs scientific research and development as well as knowledge transfer activities, such as training courses. Monte Carlo techniques, including the use of anthropomorphic and other numerical phantoms based on voxelised geometrical models, play a strong part in the activities pursued in WG 6. However, other aspects and techniques, such as neutron spectra unfolding, have an important role as well. A number of intercomparison exercises have been carried out in the past to provide information on the accuracy with which computational methods are applied and whether best practice is being followed. Within the exercises that are still ongoing, the focus has changed towards assessing the uncertainty that can be achieved with these computational methods. Furthermore, the future strategy of WG 6 also includes an extension of the scope toward experimental benchmark activities and evaluation of cross-sections and algorithms, with the vision of establishing a gold standard for Monte Carlo methods used in medical and radiobiological applications.

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“…Other IC studies with a more scientific scope and impact are also developed by EUR-ADOS WGs. The output of this work can be found in the literature, for instance, the WG12 IC on eye-lens dosemeters [31,32], the WG06 IC on computational dosimetry [33][34][35][36][37], the joint WG06 and WG07 IC on ICIDOSE [38] and other internal dosimetry issues [39][40][41], and more recently the WG07 IC on nanoparticles [42] and the WG10 IC on retrospective dosimetry using electronic components in smartphones [43][44][45]. The Learning Network (LN) is a relatively new initiative of WG02 and was organised at the AM2017 for the first time, intended to promote harmonisation of individual monitoring in Europe.…”

Section: Scientific Workhops At Ammentioning

confidence: 99%

EURADOS education and training activities

Alves¹,

Fantuzzi²,

Rühm³

et al. 2019

J. Radiol. Prot.

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This paper provides a summary of the Education and Training (E&T) activities that have been developed and organized by the European Radiation Dosimetry Group (EURADOS) in recent years and in the case of Training Courses over the last decade. These E&T actions include short duration Training Courses on well-established topics organized within the activity of EURADOS Working Groups (WGs), or one-day events integrated in the EURADOS Annual Meeting (workshops, winter schools, the intercomparison participants' sessions and the learning network, among others). Moreover, EURADOS has recently established a Young Scientist Grant and a Young Scientist Award. The Grant supports young scientists by encouraging them to perform research projects at other laboratories of the EURADOS network. The Award is given in recognition of excellent work developed within the WGs' work programme. Additionally, EURADOS supports the dissemination of knowledge in radiation dosimetry by promoting and endorsing conferences such as the individual monitoring (IM) series, the neutron and ion dosimetry symposia (NEUDOS) and contributions to E&T sessions at specific events.

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Corrigendum to “Intercomparison of dose enhancement ratio and secondary electron spectra for gold nanoparticles irradiated by X-rays calculated using multiple Monte Carlo simulation codes” [Phys. Med. 69 (2020) 147–163]

Cited by 14 publications

References 1 publication

Deposition of Gold Nanoparticles on a Self‐Supporting Carbon Foil

Deposition of Gold Nanoparticles on a Self‐Supporting Carbon Foil

Quality assurance for the use of computational methods in dosimetry: activities of EURADOS Working Group 6 ‘Computational Dosimetry’

EURADOS education and training activities

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