Corrigendum to ‘Rutaecarpine administration inhibits cancer cell growth in allogenic TRAMP-C1 prostate cancer mice correlating with immune balance in vivo’ [Biomed. Pharmacother. 139 (2021) 111648]

Yeh, Tzu-He; Lin, Jin‐Yuarn

doi:10.1016/j.biopha.2021.111751

Cited by 1 publication

(3 citation statements)

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“…After peritoneal macrophages were harvested, the spleen of each individual experiment mouse was removed aseptically to prepare single splenocytes [ 39 , 40 , 41 ]. The splenocytes suspension was adjusted to a fixed density of 1 × 10 7 cells/mL in TCM medium for following culture experiments.…”

Section: Methodsmentioning

confidence: 99%

“…Visceral tissues, including the liver, kidney, thymus, epididymal fat, spleen, and lungs, of the experiment mice were cut and weighed. Absolute (ATW, gram weight) and relative tissue weights (RTW, % of body weight) of the organs compared to the body weight of each corresponding individual experiment mouse were analyzed [ 41 ].…”

Section: Methodsmentioning

confidence: 99%

“…Levels of Th1 (IL-2 and IFN-γ)/Th2 (IL-4 and IL-5) cytokines in the BALF, levels of Th1 (IL-2 and IFN-γ)/Th2 (IL-4, IL-5 and IL-10) cytokines secreted by the splenocytes, as well as levels of pro-(IL-1β, IL-6 and TNF-α)/anti-inflammatory (IL-10) cytokines secreted by the peritoneal macrophages from the experiment mice were measured using sandwich ELISA kits (mouse DuoSet ELISA Development system, R & D Systems Inc., Minneapolis, MN, USA). The protocol was performed according to the manufacture’s instruction [ 34 , 41 ]. The limit of detection (LOD) of the ELISA kits was <15.6 pg/mL.…”

Section: Methodsmentioning

confidence: 99%

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Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice

Lin

2022

IJMS

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Menthone is rich in Mentha × Piperita L. essential oil and it has anti-inflammatory properties; research shows that it is useful, via percutaneous absorption, in treating inflammation-related diseases. However, anti-allergic inflammatory effects of volatile menthone have not yet been used to treat allergic asthma, in vivo. We hypothesized that menthone inhalation may have anti-inflammatory and anti-allergic effects in patients with allergic asthma. Therefore, in our study, menthone inhalation was used to treat ovalbumin (OVA)-sensitized and challenged asthmatic mice. Allergic inflammation mediator changes in the lungs and airways, sera, splenocytes, and peritoneal macrophages of the mice were measured. Relative expression amounts of six receptor genes related to allergic inflammation of the lungs and airways were quantitated using a two-step real time quantitative polymerase chain reaction (qPCR). Results showed that menthone inhalation increased serum OVA-specific IgG2a/IgG1 and IgG2a/IgE ratios, increased Th1-type cytokine production in the bronchoalveolar lavage fluid, and decreased nitric oxide, protein, and eotaxin levels. Menthone inhalation inhibited mast cell and eosinophil degranulation, and chemokine (C-C motif) receptor 3 (Ccr3) gene expression amounts, but (relatively) increased Th1 cytokine secretion by splenocytes. Our results evidence that menthone inhalation alleviates local and systemic allergic inflammation in asthmatic mice.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%