Corrigendum to “Syntheses and antimicrobial activities of ogipeptin derivatives” [Bioorg. Med. Chem. Lett. 42 (2021) 128093]

Practical Synthetic Method for Ogipeptin Derivatives

“…Among these 45 derivatives, some, such as compounds 1e and 1f (Figure 1 ), displayed antibacterial activities against Gram-negative bacteria in combination with a significantly reduced nephrotoxicity compared with that of colistin. 9 On the basis of these results, we surmised that the acyl side chain of ogipeptins interacts with the lipid tails of lipopolysaccharides (LPSs) and retains the ability to permeabilize the outer membrane of Gram-negative bacteria. Recently, we also succeeded in establishing a solid-phase total-synthetic route toward ogipeptins to elucidate their absolute configurations.…”