Reinforced concrete has been widely used in the last century, however, due to aggressive agents such as carbonic gas and chloride ions, it suffers premature deterioration. The concrete is a physical barrier that protects steel from corrosion, and the alkalinity of concrete leads to the formation of a passive layer around the reinforcement, which increases protection against corrosive processes. However, concrete is a porous material and has cracks that allow the entrance of aggressive agents, destabilizing the passive layer and corroding steel. The corrosion is the major cause of deterioration of concrete structures and several methods of protection and repair have been developed to increase the durability of such structures. Corrosion inhibitors, chemical substances that reduce the corrosion rate, have been widely used, both for prevention and correction. Inhibitors are classified according to their method of application, their mechanism of protection and chemical composition. In this chapter, through a literature review the main inhibitors used in reinforced concrete structures and their acting mechanisms are presented, as well as their efficiency and some side effects on concrete. It is very important to know the different types of inhibitors for correct use, thus increasing the life span of reinforced concrete structures.