Corrosive Esophagitis with Benzalkonium Chloride in a Two Days Old Neonate

Civan, Hasret Ayyıldız; Gülcü, Didem; Erkan, Tülay

doi:10.5223/pghn.2016.19.3.207

Cited by 8 publications

(9 citation statements)

References 8 publications

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“…Few cases of corrosive ingestion have been reported at 6 hours, 2 days and 2 years of age respectively. (6,7,8) Our case is unique and rare as it was given considering it as water for dilution of powder milk, but in other studies corrosives has been given accidentally considering it as sacred water (ZAM ZAM) and cough syrup respectively. In another study, a two year old baby ingested the remaining part of liquid used for hair and grease remover.…”

Section: Discussionmentioning

confidence: 92%

Corrosive ingestion in a 4 days old newborn

Sharif

Hassan²,

Munir

et al. 2022

J Pediatr Adolesc Surg

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Background: Corrosive ingestion in children is very important and sensitive issue which result in lot of morbidity and mortality corrosive ingestion is mostly in form of acid or alkali chemical. 5000 to 15000 caustic ingestion cases are reported annually in United States. Majority of cases are accidental and can occur in any age of children but in new born it occur very rarely. Case Presentation: we are presenting a case of corrosive ingestion in 04 days old new born who was given a liquid bleed mixed with formula milk by mother considering the liquid bleed as water for the dilution of milk. Conclusion: We conclude that legislation should be done for authorizes sale of corrosive chemical and awareness campaign should be lounge through social, print and electronic media about hazards of corrosive ingestion.

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Section: Discussionmentioning

confidence: 92%

Corrosive ingestion in a 4 days old newborn

Sharif

Hassan²,

Munir

et al. 2022

J Pediatr Adolesc Surg

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“…In a review of cases of both adults [ 16 , 43 , 44 ] and children [ 45 , 46 , 47 , 48 , 49 ] who survived the ingestion of BAC solutions, strictures were described in only a few neonatal cases [ 48 ]. Therefore, the positive outcome in our patient and the management or nature of the substance involved are likely not directly nor causally related.…”

Section: Discussionmentioning

confidence: 99%

“…Conversely, only three adult cases involving oral exposure to BAC have been documented ( Table 2 ). In all instances, the concentration of the BAC solution was found to be at least 10% [ 16 , 44 , 45 , 47 , 49 ], except for a single adult case where a solution with a concentration of less than 10% was ingested [ 43 ]. Currently, this case report is the only available report that suggests that even low concentrations of BAC can lead to severe symptoms.…”

Section: Discussionmentioning

confidence: 99%

Benzalkonium Chloride Poisoning in Pediatric Patients: Report of Case with a Severe Clinical Course and Literature Review

Nițescu,

Lescaie,

Boghițoiu

et al. 2024

Toxics

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The use of disinfectants, particularly those containing quaternary ammonium compounds (QUACs), has dramatically escalated globally since the coronavirus disease 2019 pandemic. We report a case that highlights the risks associated with ingesting low-concentration QUAC solutions and emphasize the importance of effective management in resolving severe lesions without sequelae. A 17-month-old boy experienced severe respiratory failure after ingesting a disinfectant containing benzalkonium chloride (BAC). The child was initially treated at a local emergency department and was subsequently transferred to a pediatric poison center. Upon evaluation, the child was found to have grade III-A corrosive esophageal lesions and chemical pneumonitis. Several complications, including massive pneumothorax and candidemia, occurred during the clinical course of the disease. However, with timely medical intervention and appropriate supportive care, the patient completely recovered without any long-term sequelae. The properties of BAC and the comprehensive management approach may have been responsible for the patient’s full recovery, despite the potentially life-threatening effects of ingesting disinfectants.

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“…However, even low concentrations of BAC can be an irritant to human skin, 3 and inappropriate usage of the disinfectant can lead to severe reactions. In another case, an infant experienced severe esophageal injury after ingesting a 10% BAC solution administered by her mother to treat the infant’s cough 5 . Ulcerative contact dermatitis and anaphylaxis to BAC‐coated catheters have also been reported 6,7 …”

Section: Discussionmentioning

confidence: 99%

Benzalkonium chloride induced corrosive balanoposthitis in a man requiring clean intermittent catheterization

et al. 2021

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Introduction Men who require intermittent catheterization may be susceptible to balanoposthitis. Benzalkonium chloride is commonly used to disinfect reusable catheters, but the concentration of this solution is critical. Case presentation A 40‐year‐old man presented with fever, pus around the glans and foreskin, and difficult catheterization. On physical examination, his urethral meatus was too narrow to insert a catheter. Suprapubic catheterization and 2 weeks of intravenous and topical treatment cured the ulcer of the glans. However, after restarting catheterization, the ulcer of the glans relapsed, and the patient’s urethral meatus was completely closed. Circumcision and incision of the meatus were performed, and antibiotics were administered. Unexpectedly, restarting catheterization caused recurrent balanoposthitis. Close inquiry revealed that the patient was using a 10% benzalkonium chloride soaking solution for a reusable catheter, which was a toxic concentration. Conclusion The disinfectant concentration should be confirmed when refractory balanoposthitis is encountered in patients who require catheterization.

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Corrosive Esophagitis with Benzalkonium Chloride in a Two Days Old Neonate

Cited by 8 publications

References 8 publications

Corrosive ingestion in a 4 days old newborn

Corrosive ingestion in a 4 days old newborn

Benzalkonium Chloride Poisoning in Pediatric Patients: Report of Case with a Severe Clinical Course and Literature Review

Benzalkonium chloride induced corrosive balanoposthitis in a man requiring clean intermittent catheterization

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