Corrosive injury to the GI tract in adults: a practical approach

Atiq, Muslim; Kibria, Rizwan; Dang, Shyam; Patel, Dhaval H; Beck, Gregory; Aduli, Farshad

doi:10.1586/egh.09.56

Cited by 9 publications

(7 citation statements)

References 47 publications

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“…In America, nearly 50% to 80% of corrosive injury incidences occur in children [ 3 , 9 , 16 , 17 ]. In Taiwan, however, only 8% of incidences were reported on persons aged 18 years and below.…”

Section: Discussionmentioning

confidence: 99%

“…The clinical features of corrosive ingestion include airway edema and stomach perforation in acute stages. Dependent upon the quantity and type of corrosive agents used and the duration of exposure, in the chronic stages, corrosive ingestion may also result in lifelong esophageal stricture and an increase in the risk of cancers and other diseases [ 1 – 3 ]. Estimations indicate that US health care organizations have spent a total of 22.9 million US dollars or 28,860 US dollars per patient for corrosive injuries in the USA [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Nationwide Population-Based Study of Corrosive Ingestion in Taiwan: Incidence, Gender Differences, and Mortality

Chen

Chung

Tsai

et al. 2016

Gastroenterology Research and Practice

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Corrosive injury results from the intake of corrosive-acid-based chemicals. However, this phenomenon is limited to a small number of cases and cannot be extrapolated to the epidemiology of corrosive injuries in actual situations. This study focuses on the annual incidence of corrosive injury and its connection to gender, risk factors, and in-hospital mortality. All patients with corrosive injury (ICD-9 947.0–947.3) were identified using a nationwide inpatient sample from 1996 until 2010. Chi-squared tests and multivariate logistic regression were used to examine risk factors of gender differences and in-hospital mortality of corrosive injury. Young adults comprised the majority of patients (71.2%), and mean age was 44.6 ± 20.9 years. Women showed a higher incidence rate of corrosive injuries, age, suicide, psychiatric disorder, and systemic complications compared with men (p < 0.001). The present study demonstrated that age (OR = 10.93; 95% CI 5.37–22.27), systemic complications (OR = 5.43; 95% CI 4.61–6.41), malignant neoplasms (OR = 2.23; 95% CI 1.37–3.62), gastrointestinal complications (OR = 2.02; 95% CI 1.63–2.51), chronic disease (OR = 1.30; 95% CI 1.08–1.56), and suicide (OR = 1.23; 95% CI 1.05–1.44) were strongly associated with in-hospital mortality. Educational programs may be helpful for reducing the incidence of ingestion of corrosive chemicals.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Nationwide Population-Based Study of Corrosive Ingestion in Taiwan: Incidence, Gender Differences, and Mortality

Chen

Chung

Tsai

et al. 2016

Gastroenterology Research and Practice

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“…The most common late complications are esophageal strictures and stenosis, gastric stenosis of the antrum and pyloris, esophageal and stomach cancer (26, 27). …”

Section: Post-corrosive Late Complicationsmentioning

confidence: 99%

Corrosive Poisonings in Adults

Chibishev¹,

Pereska²,

Chibisheva³

et al. 2012

Mater Sociomed

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Ingestion of corrosive substances may cause severe to serious injuries of the upper gastrointestinal tract and the poisoning can even result in death. Acute corrosive intoxications pose a major problem in clinical toxicology since the most commonly affected population are the young with psychic disorders, suicidal intent and alcohol addiction. The golden standard for determination of the grade and extent of the lesion is esophagogastroduodenoscopy performed in the first 12-24 hours following corrosive ingestion. The most common late complications are esophageal stenosis, gastric stenosis of the antrum and pyloris, and rarely carcinoma of the upper gastrointestinal tract. Treatment of the acute corrosive intoxications include: neutralization of corrosive agents, antibiotics, anti-secretory therapy, nutritional support, collagen synthesis inhibitors, esophageal dilation and stent placement, and surgery.

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“…Corrosive compounds are either acids or alkalis, and they cause severe acute and strictures and stenosis, gastric stenosis of the antrum and pylorus, esophageal, and stomach cancers. [1,2] Dealing with these strictures can be difficult as they are often long, tortuous and multiple. [3] Guidewire directed hollow core polyvinyl dilators like Savary-Gilliard dilators are a good way to dilate benign esophageal strictures.…”

Section: Introductionmentioning

confidence: 99%

A Clinical Study of the Use of Savary‑Gilliard Dilators in Corrosive Esophageal Strictures without the Use of Fluoroscopy: A Reality in Resource‑Limited Settings in a Developing Country

Bhatt

Kakrani

2018

Journal of Digestive Endoscopy

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Context: Corrosive compounds are either acids or alkalis, and their ingestion can cause esophageal strictures which may be tortuous and multiple. Aims: The aim of study was to assess therapeutic efficacy and safety of dilatation using Savary‑Gilliard dilators in these patients without the use of fluoroscopy. Settings and Design: A cross‑sectional observational study, conducted for 18 months in a tertiary care teaching hospital in Western India. Subjects and Methods: Ten dysphagic patients who had a history of corrosive ingestion 2 months or more before presentation, who had documented esophageal strictures on endoscopy were included. Barium swallow and endoscopy confirmed the site, length, and number of strictures. Dilatation with Savary‑Gilliard dilators was done without the use of fluoroscopy with the help of guide wire in “rule of threes.” Patients were followed up immediately and for 12 months. Descriptive statistics, mean, and SD were applied in EPI info version 7 software. Results: The mean age of 29 + 6.5 years and 70% were females. About 80% had dysphagia Grades III and IV. On endoscopy, 40% had strictures at multiple sites and 60% of patients had strictures more than 5 cm in length. 50% strictures were very tight. Number of patients in whom there was the passage of one dilator more than the stricture in the first session were 80%. A mean of 8.28 sessions of dilatation were required. Adequate dysphagia relief was achieved in 8 (80%) patients, while there were 2 failures. A total of 180 dilatations were performed on these 10 patients of corrosive strictures over a period of 12 months. One minor perforation occurred in this study. Conclusions: In resource‑limited settings such as India, dilatation without fluoroscopy can be considered as effective and safe initial management for corrosive strictures.

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Corrosive injury to the GI tract in adults: a practical approach

Cited by 9 publications

References 47 publications

A Nationwide Population-Based Study of Corrosive Ingestion in Taiwan: Incidence, Gender Differences, and Mortality

A Nationwide Population-Based Study of Corrosive Ingestion in Taiwan: Incidence, Gender Differences, and Mortality

Corrosive Poisonings in Adults

A Clinical Study of the Use of Savary‑Gilliard Dilators in Corrosive Esophageal Strictures without the Use of Fluoroscopy: A Reality in Resource‑Limited Settings in a Developing Country

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