Corrosivity of N-methyl pyrrolidone in solvent treatment of oils

Вишневский, А. В.; Konoplev, V. P.; Kravchenko, Z. A.; Shreider, A. V.; Shen-u-Shen, Yu. K.; Fateeva, T. V.

doi:10.1007/bf00731919

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2010

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“…Apart from the useful properties of NMP, some deleterious effects have also been found. Steel parts of apparatuses used in the presence of this solvent have been reported to undergo a corrosive reaction at temperatures above 300° C, which restricts its applications at higher temperatures in a metal-containing setup (12,13).…”

Section: Physicochemical Propertiesmentioning

confidence: 99%

Review of Pharmaceutical Applications of N-Methyl-2-Pyrrolidone

Jouyban

Fakhree

Shayanfar³

2010

J Pharm Pharm Sci

160

112

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N-Methyl-2-pyrrolidone (NMP) or Pharmasolve is very strong solubilizing agent and it has important applications in different fields of industry. This review presents NMP physicochemical characteristics, application especially in pharmaceutical sciences, pharmacokinetic and toxicity. Characteristics of NMP such as physicochemical properties, solubilization efficacy, toxicity and adverse effects were compared with other common solvents used in the pharmaceutical industries. This review reveals that NMP is an acceptable pharmaceutical solvent and its efficacy, toxicity, and side effects are comparable with other common solvent.

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Section: Physicochemical Propertiesmentioning

confidence: 99%