The present research work investigated on the behavior of corrugated core composite sandwich panel (CCCS) with composite face-sheets reinforced by pseudo-elastic NiTi shape memory alloy (SMA) wires subjected to high-velocity impact experimentally. The number of SMA wires, their location, and their pre-strain percentage are the parameters studied in this investigation. The sandwich specimens were made by woven glass fibers/epoxy composite face-sheets strengthened by the SMA wires and Aluminum corrugated core and prepared using the wet hand lay-up method. Their behavior is evaluated under high-velocity impact test by a gas gun impactor testing machine. According to the results obtained, a significant change in the amount of energy absorption of the specimens containing SMA wires is observed. By increasing the number of the SMA wires, the energy absorption by the specimen is increased, but by pre-straining the SMA wires, the effect in energy absorption is significant. Also, when the projectile hits the SMA wire in CCCS, better properties in energy absorption can be observed. The results show that the energy absorption increased from 117.247 J for the specimen without the SMA wire to 128.749 J for the six SMA wires specimen. On the other hand, by applying the pre-strain to the SMA wires, the residual stresses in the specimens and hence the energy absorption in the specimen with six SMA wires with 3% pre-strain increased to 142.57 J.