Cortical Regulation During the Early Stage of Initiation of Voluntary Swallowing in Humans

Watanabe, Yutaka; Abe, Shinichi; Ishikawa, Tatsuya; Yamada, Yoshiaki; Yamane, Gen-yuki

doi:10.1007/s00455-003-0509-5

Cited by 71 publications

(49 citation statements)

References 38 publications

(51 reference statements)

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“…32 A magnetoencephalographic study demonstrated consistent long-lasting activation of the insular cortex before swallowing. 33 Taken together we posit a major role of the insula in elevating the risk of aspiration as it may function as a key area in the regulation of both voluntary and automatic swallowing.…”

Section: Neuroanatomical Predictors Of Acute Risk Of Aspirationmentioning

confidence: 84%

Lesion Location Predicts Transient and Extended Risk of Aspiration After Supratentorial Ischemic Stroke

Galovic

Leisi

Müller

et al. 2013

Stroke

103

108

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Section: Neuroanatomical Predictors Of Acute Risk Of Aspirationmentioning

confidence: 84%

Lesion Location Predicts Transient and Extended Risk of Aspiration After Supratentorial Ischemic Stroke

Galovic

Leisi

Müller

et al. 2013

Stroke

103

108

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“…In the SMA, the pre-SMA receives input signals from the cingulate gyrus and the prefrontal area 17) . In addition, Watanabe et al 31) reported that the islet is closely associated with preparation of swallowing motions and that the cingulate gyrus is involved in the actual performance of swallowing; further studies using new methods will be required to confirm these results.…”

Section: Activated Brain Areas 1) Supplementary Motor Areamentioning

confidence: 99%

Visual and Auditory Stimuli Associated with Swallowing: An fMRI Study

Kawai

Watanabe

Tonogi

et al. 2009

Bull. Tokyo Dent. Coll.

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We focused on brain areas activated by audiovisual stimuli related to swallowing motions. In this study, three kinds of stimuli related to human swallowing movement (auditory stimuli alone, visual stimuli alone, or audiovisual stimuli) were presented to the subjects, and activated brain areas were measured using fMRI and analyzed. When auditory stimuli alone were presented, the supplementary motor area was activated. When visual stimuli alone were presented, the premotor and primary motor areas of the left and right hemispheres and prefrontal area of the left hemisphere were activated. When audiovisual stimuli were presented, the prefrontal and premotor areas of the left and right hemispheres were activated. Activation of Broca's area, which would have been characteristic of mirror neuron system activation on presentation of motion images, was not observed; however, activation of brain areas related to swallowing motion programming and performance was verified for auditory, visual and audiovisual stimuli related to swallowing motion. These results suggest that audiovisual stimuli related to swallowing motion could be applied to the treatment of patients with dysphagia.

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“…Numerous techniques have been applied to investigate functional brain activity during swallowing (primarily in healthy individuals), including positron emission tomography (PET) [31][32][33][34], magnetoencephalography (MEG) [35][36][37][38][39], transcranial magnetic stimulation (TMS) [31,[40][41][42], and electroencephalography [43][44][45] (EEG). Functional MRI (fMRI) has been especially useful in studying brain activity during swallowing in normal individuals, mainly because of its high spatial and temporal resolution (ability to detect changes in an image across different spatial locations and over time) for various tissue types, its lack of use of radiation or need for other invasive procedures (needle injections), and its ability to obtain images in any plane [46].…”

mentioning

confidence: 99%

Normal Swallowing and Functional Magnetic Resonance Imaging: A Systematic Review

2007

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Unknowns about the neurophysiology of normal and disordered swallowing have stimulated exciting and important research questions. Previously, these questions were answered using clinical and animal studies. However, recent technologic advances have moved brain-imaging techniques such as functional magnetic resonance imaging (fMRI) to the forefront of swallowing neurophysiology research. This systematic review has summarized the methods and results of studies of swallowing neurophysiology of healthy adults using fMRI. A comprehensive electronic and hand search for original research was conducted, including few search limitations to yield the maximum possible number of relevant studies. The participants, study design, tasks, and brain image acquisition were reviewed and the results indicate that the primary motor and sensory areas were most consistently active in the healthy adult participants across the relevant studies. Other prevalent areas of activation included the anterior cingulate cortex and insular cortex. Review limitations and suggested future directions are also discussed. KeywordsDeglutition; Deglutition disorders; Functional magnetic resonance imaging An estimated 18 million adults have dysphagia, or swallowing disorders, in the United States [1]. Dysphagia is a condition that becomes more prevalent with increasing age and often results from neurologic damage or disorders such as stroke, Alzheimer's disease, and Parkinson's disease. As a result, much of the research on swallowing disorders has focused on understanding and delineating the neurophysiology of swallowing with the overall goal of increasing the efficacy and accuracy with which diagnosis and intervention procedures are employed.Data from clinical and animal studies have provided the earliest insight into the central control of swallowing. In particular, clinical studies have provided an evolving foundation of thought pertaining to the central control of swallowing. These investigations have characteristically started with a disordered neurologic group (i.e., poststroke population) and combined both anatomical brain-imaging techniques (still pictures of the brain) such as computerized tomography (CT) and/or magnetic resonance imaging (MRI) with a swallowing assessment to correlate damaged brain areas with the presence or type of dysphagia observed. The vast majority of clinical studies have focused on the effects of stroke on swallowing [2][3][4][5][6][7][8][9][10][11][12][13][14][15] This systematic review summarizes studies that have explored the neurophysiology of swallowing in healthy adults using fMRI. The goal of a systematic review is to gather and present objectively the current status of research in a particular area of interest. It presents an unbiased review of the relevant literature by describing the systematic methods for obtaining the relevant literature on this topic. Search Strategies ElectronicAn electronic database search was completed using Medline (Ovid and PubMed), CINAHL, DARE, ACP Journal Club, the Cochrane L...

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Cortical Regulation During the Early Stage of Initiation of Voluntary Swallowing in Humans

Cited by 71 publications

References 38 publications

Lesion Location Predicts Transient and Extended Risk of Aspiration After Supratentorial Ischemic Stroke

Lesion Location Predicts Transient and Extended Risk of Aspiration After Supratentorial Ischemic Stroke

Visual and Auditory Stimuli Associated with Swallowing: An fMRI Study

Normal Swallowing and Functional Magnetic Resonance Imaging: A Systematic Review

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