Cortical vein thrombosis in adult patients of cerebral venous sinus thrombosis correlates with poor outcome and brain lesions: a retrospective study

Liang, Jianhua; Chen, Hongbing; Li, Zhuhao; He, Shiliang; Luo, Boning; Tang, Shujin; Shang, Wenjin; Zeng, Jinsheng

doi:10.1186/s12883-017-0995-y

Cited by 23 publications

(40 citation statements)

References 17 publications

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“…Our findings are partially consistent with those of previous researchers, but there are some discrepancies (5,13). According to their studies, seizure, FND, altered consciousness, venous infarction, ICH, SAH, and concurrent SSS thrombosis were more frequent in the CVI group than in the CVI negative group (5,13) and the mRS score at discharge was higher for the CVI group than the CVI-negative group (5). Although we cannot accurately explain why our results differ from those of other researchers, it might be caused by differences in the patient population.…”

Section: Discussionsupporting

confidence: 92%

“…They reported 3.4% -23% incidence of CVI. However, according to a recent study of Liang et al, CVI was present in 61.4% of their patients (5). The difference in the frequency of CVI in each study might be caused by various factors, which are differences in patient population, imaging techniques, and reader's experience in imaging interpretation.…”

Section: Discussionmentioning

confidence: 91%

“…Recently, the diagnosis of CV thrombosis has been increasing with the emergence of advanced imaging techniques. According to a recent study of Liang et al (5), CV thrombosis is common and is associated with severe clinical and radiological manifestations and poor clinical outcomes. However, they have not yet been fully established.…”

Section: Introductionmentioning

confidence: 99%

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Clinical and Radiological Manifestations of Cerebral Venous Thrombosis: Are There Any Differences According to Presence or Absence of Cortical Vein Involvement?

et al. 2018

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Background: Cerebral venous thrombosis (CVT) is difficult to diagnose because of the variety of its clinical and imaging findings and the many anatomical variations in the cerebral venous system. Objectives: We aimed to investigate the clinical and radiological CVT and to evaluate differences in their findings, according to the presence or absence of cortical vein involvement (CVI). Patients and Methods: From the 13 years database of our institution, forty-nine patients were enrolled in the study. In all patients, CVT was confirmed on CT venography, MR venography and/or digital subtraction angiography (DSA). We retrospectively reviewed the clinical presentations and CT and MR findings of the patients and compared their findings, according to the presence or absence of CVI. Results: CVI was detected in 31 patients (63.3%). The most common clinical symptom was headache (61.2%), followed by focal neurologic deficit (FND) (49.0%), seizure (40.8%), and altered consciousness (18.4%). FND was frequent in the CVI group (67.7 vs. 16.7%, P = .001). On CT (n = 49) and/or MR (n = 38), intracranial hemorrhage was present in 33 patients (67.3%) and parenchymal hyperintensity was detected in 24/38 (63.2%). Subarachnoid hemorrhage (SAH) was frequent in the CVI group (51.6 vs. 16.7%, P = .018). The cortical vein (CV) was the most common site of CVT (63.3%), followed by superior sagittal (61.2%), transverse (53.1%), sigmoid (42.9%), and straight (20.4%) sinuses. The superior sagittal sinus thrombosis was frequently associated with concomitant CV thrombosis (74.2 vs. 38.9%, P = .032). Conclusion: CVT commonly involved the CV. Although its clinical manifestation was diverse, FND was common in the CVI group. Intracranial hemorrhage and parenchymal hyperintensity were common CT and MR findings and SAH was commonly associated in the CVI group.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 91%

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Clinical and Radiological Manifestations of Cerebral Venous Thrombosis: Are There Any Differences According to Presence or Absence of Cortical Vein Involvement?

et al. 2018

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“…In a recent study of 44 patients with CVST, concomitant cortical vein thrombosis was associated with severe clinical manifestations, poor short-term outcomes, and brain lesions. [ 25 ] SAH has rarely been reported in association with CVST. One patient was described by Sztajzel et al .…”

Section: Discussionmentioning

confidence: 99%

Clinical presentation, neuroimaging findings, and predictors of brain parenchymal lesions in cerebral vein and dural sinus thrombosis: A retrospective study

Goyal¹,

Charan²,

Singh³

2018

Ann Indian Acad Neurol

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Introduction:Cerebral venous sinus thrombosis (CVST) is an unusual cause of stroke with potentially serious consequences. This study was designed to investigate the clinical and neuroimaging features in patients with CVST and to analyze the predictors of brain parenchymal lesions.Materials and Methods:A retrospective study of 181 patients with CVST was conducted in a tertiary care hospital.Results:Of 181 patients (age range 14–96 years, mean age: 34.64 ± 14.66 years), 121 were female (66.9%). Most of the patients were in their third decade of life. Headache (47.51%) was the most common clinical presentation followed by seizures (24.31%). Transverse sinus (TS) (77.9%) was the most common site of venous sinus thrombosis. Brain parenchymal lesions were present in 63%, and each patient had subarachnoid and intraventricular hemorrhage. Hemorrhagic venous infarct was the most common brain parenchymal lesion (37.57%). Frontal region (25.4%) was the most common site of brain parenchymal lesions followed by frontoparietal region (21.9%). Women were more likely to have brain parenchymal lesions (72.4%, P = 0.034). Headache was the most common clinical presentation in patients without brain parenchymal lesions while seizures with brain parenchymal lesions. Straight sinus thrombosis was more likely to be associated with brain parenchymal lesions (P = 0.009).Conclusion:CVST presents in young and more commonly in females. TS was the most common site of venous sinus thrombosis. Female gender, seizures, altered sensorium and focal neurological deficit at presentation, and straight sinus thrombosis were more likely associated with the presence of brain parenchymal lesions.

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“…В ретроспективном исследовании J. Liang и соавт. [15] были получены следующие данные: тромбоз верхнего сагиттального синуса встречался в 72,7% случаев, левого поперечного синусав 43,2%, левого сигмовидного синуса -в 43,2%, правого поперечного -в 36,4%, правого сигмовидного -в 36,4%, прямого синуса -в 9,1%. В 47,7% случаев тромбоз МВ и ВС сопровождался вторичными изменениями мозга (инфаркты выявлены в 43,2% случаев, кровоизлияния -в 27,3%).…”

Section: локализацияunclassified

Clinical presentations, diagnosis and treatment of cerebral vein and sinus thrombosis

Maksimova

Dubovitskaya

Шувахина

2018

Z. nevrol. psikhiatr. im. S.S. Korsakova

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The problem of thrombosis of cerebral veins and venous sinuses is insufficiently studied. The real incidence of cerebral venous thrombosis remains incompletely defined. The article presents results of clinical research on cerebral vein and sinus thrombosis, which served as a ground for an analysis of causes and development of the disease. In 20-35% of patients with cerebral venous thrombosis, this disease remains idiopathic after extensive investigation. Particular attention is given to risk factors, clinical presentations, early diagnosis, treatment, prognosis of cerebral vein and sinus thrombosis.

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Cortical vein thrombosis in adult patients of cerebral venous sinus thrombosis correlates with poor outcome and brain lesions: a retrospective study

Cited by 23 publications

References 17 publications

Clinical and Radiological Manifestations of Cerebral Venous Thrombosis: Are There Any Differences According to Presence or Absence of Cortical Vein Involvement?

Clinical and Radiological Manifestations of Cerebral Venous Thrombosis: Are There Any Differences According to Presence or Absence of Cortical Vein Involvement?

Clinical presentation, neuroimaging findings, and predictors of brain parenchymal lesions in cerebral vein and dural sinus thrombosis: A retrospective study

Clinical presentations, diagnosis and treatment of cerebral vein and sinus thrombosis

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