2017
DOI: 10.3928/01477447-20161116-07
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Corticosteroid Injections: A Review of Sex-Related Side Effects

Abstract: Corticosteroid injections are used as a nonoperative modality to combat acute inflammation when conservative treatments fail. As female patients are regularly seen by orthopedic physicians, it is essential to identify and understand potential sex-related side effects. The aim of this article is to examine available literature for sex-related side effects of orthopedic-related corticosteroid injections. Although the incidence is low, sex-related side effects, such as abnormal menstruation, lactation disturbance… Show more

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Cited by 12 publications
(14 citation statements)
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“…18 An investigation performed in 1999 estimated that infection occurs in 4.6 of every 100 000 intra-articular corticosteroid injections, a 0.0046% incidence rate. 3,18 Interestingly, in our cohort, no patient developed a postinjection infection, but this may be due to a lack of sufficient power. It is also notable that no anaphylactic reactions were seen either, even though this has been reported in the literature as a potential side effect and has been observed shortly after injection in one patient who required resuscitation years ago by the senior author.…”
Section: Discussionmentioning
confidence: 76%
See 1 more Smart Citation
“…18 An investigation performed in 1999 estimated that infection occurs in 4.6 of every 100 000 intra-articular corticosteroid injections, a 0.0046% incidence rate. 3,18 Interestingly, in our cohort, no patient developed a postinjection infection, but this may be due to a lack of sufficient power. It is also notable that no anaphylactic reactions were seen either, even though this has been reported in the literature as a potential side effect and has been observed shortly after injection in one patient who required resuscitation years ago by the senior author.…”
Section: Discussionmentioning
confidence: 76%
“…Previous studies investigating outcomes after corticosteroid injections have used a more heterogeneous anatomic location among their study population, which may have biased study results. 3,9,19,21,23 An example hereof is a study by Kumar and Newman, included 672 patients receiving intra-articular or extra-articular injections of the knee, elbow, wrist, shoulder, foot, ankle, finger, or hip. 17 Another type of heterogeneity is caused by previous studies that did not distinguish between intra-articular or extra-articular corticosteroid injections.…”
Section: Discussionmentioning
confidence: 99%
“…They are clinically very effective in reducing joint inflammation, erythema, edema, and acute pain, as well as increasing joint motility. The most commonly used corticosteroids are triamcinolone acetonide, methylprednisolone acetate, betamethasone acetate and disodium phosphate, as well as dexamethasone [11]. Such steroids are used for various conditions, such as asthma [3], atopy, dermatitis [12], rheumatism [2], allergies and cancers [13], as well as pain.…”
Section: Discussionmentioning
confidence: 99%
“…It’s effective in reducing edema and pain in the short term but not persistent (Huisstede et al, 2010). In addition, specific females related side effects have been reported (Brook et al, 2017). The taping, which serves as a support for the wrist, pulls around the wrist to reduce excessive pressure on the carpal tunnel and induce proper relaxation (Lund and Amadiol, 2006).…”
Section: Introductionmentioning
confidence: 99%