2020
DOI: 10.29374/2527-2179.bjvm106520
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Corticosteroid use in neurology: how dogs are referrals to a neurology service?

Abstract: Corticosteroids are drugs widely used in veterinary neurology due to their recognized anti-inflammatory, immunosuppressive and analgesic effects. However, their use in high doses and for long term may result in undesirable side effects. This study describes the prevalence of dogs with neurologic diseases referred to a veterinary neurology service with previous prescriptions for corticosteroids. In this retrospective study 284 medical records of dogs were evaluated in the period between August 2017 and April 20… Show more

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“…In this report, despite clear evidence pointing to an acute SRMA, we chose not to administer immunosuppressive dose of corticosteroids before the results of infectious disease serologies and bacterial culture were available. Dexamethasone at 0.15 mg/kg/24 hours IV has been described in human medicine for the treatment of bacterial diseases of the CNS to decrease intracranial pressure, decrease CNS inflammation and lower the risk of neurologic sequelae 25 . In small animals, immunosuppression is generally accomplished with prednisolone at 2.2−6.6 mg/kg/24 hours or the equipotent dosage of dexamethasone at 0.33−1.1 mg/kg/24 hours 26 .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…In this report, despite clear evidence pointing to an acute SRMA, we chose not to administer immunosuppressive dose of corticosteroids before the results of infectious disease serologies and bacterial culture were available. Dexamethasone at 0.15 mg/kg/24 hours IV has been described in human medicine for the treatment of bacterial diseases of the CNS to decrease intracranial pressure, decrease CNS inflammation and lower the risk of neurologic sequelae 25 . In small animals, immunosuppression is generally accomplished with prednisolone at 2.2−6.6 mg/kg/24 hours or the equipotent dosage of dexamethasone at 0.33−1.1 mg/kg/24 hours 26 .…”
Section: Discussionmentioning
confidence: 99%
“…Dexamethasone at 0.15 mg/kg/24 hours IV has been described in human medicine for the treatment of bacterial diseases of the CNS to decrease intracranial pressure, decrease CNS inflammation and lower the risk of neurologic sequelae. 25 In small animals, immunosuppression is generally accomplished with prednisolone at 2.2−6.6 mg/kg/24 hours or the equipotent dosage of dexamethasone at 0.33−1.1 mg/kg/24 hours. 26 The clinical deterioration 12 hours after treatment induction was, therefore, considered to be related to the progression of the septic arthritis, rather than induced by corticosteroid administration.…”
Section: Discussionmentioning
confidence: 99%