Corticotrophins and corticosteroids

Dukes, M. N. G.

doi:10.1016/s0378-6080(81)80045-1

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Was Die Lokale Anwendung Von Rhinologika Auf Die1

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1986

2009

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Cited by 6 publications

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“…Antihistaminzusätze zu Nasentropfen können gelegentlich zu Abgeschlagenheit, Müdigkeit und Arbeitsunlust der Patienten führen. Bei langdauernder intranasaler Glucocorticoidtherapie muI mit der Moglichkeit einer atrophischen Rhinitis und gelegentlichen Septumperforationen gerechnet werden (17,32). Bei langerdauernder lokaler Applikation von Flunisolid wurden Geruchstorungen (48) und Nasenfötor infolge Candida-albicans-Befall beschrieben (56).…”

Section: Was Die Lokale Anwendung Von Rhinologika Auf Dieunclassified

Arzneimittelnebenwirkungen auf die Nasenschleimhaut und den Geruchssinn*

Gastpar¹

1986

Laryngo-Rhino-Otol

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Section: Was Die Lokale Anwendung Von Rhinologika Auf Dieunclassified

Arzneimittelnebenwirkungen auf die Nasenschleimhaut und den Geruchssinn*

Gastpar¹

1986

Laryngo-Rhino-Otol

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Effect of Combined Prednisolone, Epidural Analgesia, and Indomethacin on the Systemic Response After Colonic Surgery

Schulze

Sommer²,

Bigler³

et al. 1992

Arch Surg

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Twenty patients undergoing colonic resection were randomized to either conventional postoperative pain treatment with morphine chloride and acetaminophen (group 1, n = 9) or methylprednisolone sodium succinate 90 minutes before surgery plus intraoperative neural blockade, with a postoperative analgesic regimen with combined bupivacaine hydrochloride-morphine and indomethacin sodium for systemic effect (group 2, n = 11). Assessments of pain, pulmonary function, convalescence, and various injury factors were done several times until 8 days after surgery. Postoperative pain and hyperthermic response were eliminated in group 2. Conventional reduction in pulmonary function measures was improved in group 2, and fatigue and mobility were less pronounced. Prostaglandin E2, interleukin 6, and C-reactive protein levels increased in both groups, but significantly less in group 2. These results suggest that a combined neural and humoral blockade may more effectively inhibit the global stress response to elective surgery than previously observed with neural blockade with or without indomethacin.

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