Corynebacterium hemolyticum Peritonsillar Abscess Mimicking Diphtheria

Kovatch, Anthony L.; Schuit, Kenneth E.; Michaels, Richard H.

doi:10.1001/jama.1983.03330370067037

Cited by 19 publications

(1 citation statement)

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“…The CDC does not have a single human isolate in their collection (87). Furthermore, as already mentioned, Jackman et al found that two of four human isolates received as C. bovis were, in fact, C. jeikeium; the other two were not further identified (93 (207,248); (ii) a report that it was a mutant of C. pyogenes (10); (iii) the description of a positive catalase test that is not observed with conventional testing methods (10); (iv) a major reference manual's statement (35) that most strains reduce nitrate to nitrite, which is not true of isolates from most regions of the world (45,60,80,110,176,240); and (v) the lack of hemolysis after 24 h on sheep blood agar, the medium used by >95% of clinical laboratories in this country. Nevertheless, A. haemolyticum can now be distinguished reliably from other coryneform groups on the basis of colonial morphology and conventional biochemical tests (45).…”

Section: Fluorescent Diphtheroidsmentioning

confidence: 99%

Coryneform bacteria in infectious diseases: clinical and laboratory aspects

1990

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Coryneform isolates from clinical specimens frequently cannot be identified by either reference laboratories or research laboratories. Many of these organisms are skin flora that belong to a large number of taxonomic groups, only 40% of which are in the genus Corynebacterium. This review provides an update on clinical presentations, microbiological features, and pathogenic mechanisms of infections with nondiphtheria Corynebacterium species and other pleomorphic gram-positive rods. The early literature is also reviewed for a few coryneforms, especially those whose roles as pathogens are controversial. Recognition of newly emerging opportunistic coryneforms is dependent on sound identification schemes which cannot be developed until cell wall analyses and nucleic acid studies have defined the taxonomic groups and all of the reference strains within each taxon have been shown by molecular methods to be authentic members. Only then can reliable batteries of biochemical tests be selected for distinguishing each taxon.

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