Cosmetic Procedures in the Treatment of Alopecia

Kartal, Selda Pelin; Altunel, Cemile Tuğba; Gençler, Bilgen

doi:10.5772/66747

Cited by 3 publications

(2 citation statements)

References 116 publications

(192 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Trichoscopic findings at the beginning and conclusion of the sixth month were significantly different in the Botox group ( p = 0.01), while this difference was extremely significant in the LC group ( p = 0.009). This coincides with Kartal et al 11 His study was on 30 patients with AGA; they studied 15 people given 5% Capixyl lotion and 15 people given a placebo for 4 months and discovered that Capixyl increased anagen hair density while reducing telogen density more than the placebo. This was explained by Talavera‐Adame et al 12 as they suggested that a direct action of Capixyl on 5‐a‐reductase helps prevent hair shrinkage by modulating dihydrotestosterone.…”

Section: Discussionsupporting

confidence: 80%

Efficacy of botulinum toxin A injection in the treatment of androgenic alopecia: A Comparative Controlled Study

Nassar

Abdel-Aleem

Samir

et al. 2022

J of Cosmetic Dermatology

View full text Add to dashboard Cite

Introduction Scalp injection with mesotherapy (LC cell hair essence) helps in anchoring hair follicles and might have good therapeutic efficacy and lower side effects than Botox in the treatment of androgenetic alopecia (AGA). Objective To assess the trichoscopy and the clinical therapeutic response of LC hair essence serum injection vs. botulinum toxin (A) injection in the treatment of androgenetic alopecia. Patients and methods Sixty‐two AGA patients were included in the present study. Group I consisted of 31 patients who were injected with 1 ml of LC hair essence serum diluted with 0.5 ml of 0.9% normal saline once weekly for 8 weeks, and Group II involved 31 patients who were injected with 50 units of botulinum toxin A. Trichoscopic examination and photo documentation were done for every case before starting treatment (baseline) and after treatment with monthly follow‐up to the patients. Results There was a significant difference between baseline trichoscopy findings and at the end of sixth month in Botox group, and the difference was highly significant in LC group; there was a statistically significant increase in the frequency of side effects (irritation and headache) among Group II compared with that of Group I. Conclusion Botox can induce significant results in the treatment of AGA with mild and tolerable side effects but with high cost, while LC hair serum exhibit excellent results with fewer side effects.

show abstract

Section: Discussionsupporting

confidence: 80%

Efficacy of botulinum toxin A injection in the treatment of androgenic alopecia: A Comparative Controlled Study

Nassar

Abdel-Aleem

Samir

et al. 2022

J of Cosmetic Dermatology

View full text Add to dashboard Cite

show abstract

“…Hyperkeratosis (scaling), pruritus, alopecia (hair loss) and inflammatory signs (erythema) are common symptoms of scalp disorders often related to a greater susceptibility of the scalp to bacterial or mycotic infections [28]. Scalp microbiome analyses showed that the most abundant bacteria found in the scalp are C. acnes, S. aureus and S. epidermidis; M. furfur is among the most common cutaneous commensal fungi of the scalp [29,30]. On undamaged skin, this resident microbiome provides a benefit to skin integrity and is considered non-pathological.…”

Section: Discussionmentioning

confidence: 99%

Biological Efficacy Evaluation of a Non-Cross-Linked Hyaluronic Acid Dermal Filler for Biomedical Application in Inflammatory Scalp Conditions

Sommatis

Capillo

Liga

et al. 2021

Life

View full text Add to dashboard Cite

(1) Background: The dysbiosis of some cutaneous commensal microorganisms is the trigger factor for the activation of the inflammatory cascade by keratinocytes in many skin disorders. Mesotherapy is an innovative technique for many scalp disorders, with the function of restoring the physiology of the skin. (2) Methods: the antimicrobial, antibiofilm and anti-inflammatory activity of the non-cross-linked HA formulation (Hydro Deluxe, Matex Lab S.p.a., Brindisi, Italy) was investigated against the most common microorganisms of the scalp (Staphyloccoccus epidermis, Staphyloccoccus aureus, Cutibacterium acnes and Malassezia furfur). Anti-inflammatory activity was evaluated on an internal 3D model of Reconstructed Human Epidermis (RHE) inserts infected with the strains as pro-inflammatory stimulus. (3) Results and Conclusions: the data collected showed a good antimicrobial and antibiofilm activity against all selected strains. The HA-based formulation did not show cytotoxicity on RHE, either alone or in presence of the infectious stimulus. The analysis of the expression of Interleukin (IL)-8 levels showed an excellent ability to reduce this pro-inflammatory marker. Overall, the efficacy assessment of the formulation supported its potential effectiveness in mesotherapy for the treatment of scalp disorders.

show abstract

The impact of monotherapies for male androgenetic alopecia: A network meta‐analysis study

Gupta,

Bamimore,

Wang

et al. 2024

J of Cosmetic Dermatology

View full text Add to dashboard Cite

BackgroundThe evidence base pertaining to the efficacy of monotherapies for androgenetic alopecia (AGA), the most common form of hair loss, is ever expanding—and this warrants a formal comparison therapies' effect on a frequent basis.AimsThe objective of the current study was to determine the comparative effect of relevant monotherapies for male AGA.Patients/MethodsOur aim was achieved by conducting Bayesian network meta‐analysis (NMA), under a random effects model, for two outcomes: 6‐month change in (1) total and (2) terminal hair density in adult (i.e., aged 18 years and above) men with AGA; these analyses were preceded by a systematic search of the peer‐reviewed literature for suitable data. Interventions' surface under the cumulative ranking curve (SUCRA) and pairwise relative effects (quantified as mean differences) were estimated through the NMAs.ResultsWe determined the comparative effect of 20 active comparators and a control (i.e., placebo/vehicle). “Dutasteride 0.5 mg once daily for 24 weeks” was ranked the most effective in terms of 6‐month change in (1) total hair density (SUCRA = 87%) and terminal hair density (SUCRA = 98%). Our results showed that interventions’ effectiveness can be dose dependent.ConclusionsOur updated analyses of the up‐to‐date evidence regarding monotherapies for male AGA showed that the oral form of 5‐alpha reductase inhibitors are more effective than oral minoxidil and other newer agents like Botox, microneedling, and photobiomodulation. Our findings can better inform clinical decision making and design of future research studies.

show abstract

Cosmetic Procedures in the Treatment of Alopecia

Cited by 3 publications

References 116 publications

Efficacy of botulinum toxin A injection in the treatment of androgenic alopecia: A Comparative Controlled Study

Efficacy of botulinum toxin A injection in the treatment of androgenic alopecia: A Comparative Controlled Study

Biological Efficacy Evaluation of a Non-Cross-Linked Hyaluronic Acid Dermal Filler for Biomedical Application in Inflammatory Scalp Conditions

The impact of monotherapies for male androgenetic alopecia: A network meta‐analysis study

Contact Info

Product

Resources

About