Abstract.We study a novel proposal for the origin of cosmological cold dark matter (CDM) which is rooted in the quantum nature of spacetime. In this model, off-shell modes of quantum fields can exist in asymptotic states as a result of spacetime nonlocality (expected in generic theories of quantum gravity), and play the role of CDM, which we dub off-shell dark matter (Of DM). However, their rate of production is suppressed by the scale of non-locality (e.g. Planck length). As a result, we show that Of DM is only produced in the first moments of big bang, and then effectively decouples (except through its gravitational interactions). We examine the observational predictions of this model: In the context of cosmic inflation, we show that this proposal relates the reheating temperature to the inflaton mass, which narrows down the uncertainty in the number of e-foldings of specific inflationary scenarios. We also demonstrate that Of DM is indeed cold, and discuss potentially observable signatures on small scale matter power spectrum.