The aim of the research is to determine the characteristics of the connection between the technical and the anthropological in the philosophical concepts of P. Florensky, F. Dessauer and in the literary activity of A. Platonov. The question of the human dimension of technology is essential today, it is associated with the discussion about the genesis of technology, its role in society, the prospects for the human civilization development and the need to regulate technological progress.The use of the comparative method allows to focus on the specifics of understanding the issue of the relationship between human being and technology in the works of P. Florensky, F. Dessauer and A. Platonov, as well as to consider the differences between the repercussions of the topic technology and human being in philosophy and literature. The Russian religious philosopher P. Florensky expanded the understanding of the technology essence up to the space of culture and the achievement of harmony set by God and lost by man. The connection between the genesis of technology and the capacity of Being to coming into being is determined by the works of the German philosopher and theologian F. Dessauer. In science fiction stories and short novels by A. Platonov and, in general, in his early works there may be viewed the fascination with the human mind and the scientific invention generated by it. However, there are also doubts concerning the possibility of the projects implementation created by the narrowed consciousness of a human being: the loneliness of characters-transformers (creators), the tragedy during the projects implementation, the discovery of the innermost areas of human existence.It is necessary to address the fundamental problem of relations between the anthropological and the technical in the cultures system in order to understand the nature of technology, its place in the sphere of culture, and its functions in the sphere of society.