“…The introduction of drugs able to control hyperacidity and the radical treatment of HP made possible by antibiotics have led on the one hand to a reduced need for acid-reductive surgery and on the other hand a reduction of ulcerative recurrences (and so the need for re-intervention surgery) [43,44,59]. Nevertheless, up to 35% of patients who have undergone PPU may require definitive surgical treatment, which may be conducted laparoscopically in relation to the degree of the surgeon's skill, considering also the overlapping results which compare the open technique: recurrence of the ulcer from 4 to 11%; post-op complications 1-2% [12,13].…”