The need for digital support of decisions taken in agriculture is a prerequisite for this industry transformation and development. One of the main directions in solving these issues is the use of end-to-end technologies, as well as convenient and effective economic and mathematical tools. In this regard, research in the development of economic and mathematical models and decision support tools, analysis and forecasting for the agro-industrial complex is relevant. In addition to supporting agriculture in general, attention should be paid to addressing issues of improving the efficiency of agricultural activities themselves; new effective methods and approaches introduction is of particular importance in this issue, the use of which will increase the industry attractiveness, promote import substitution, improve the quality of agricultural products, etc. The agricultural pests entomophages natural complexes use can be considered as one of the approaches to improving the “purity” of agricultural products due to the rejection (complete or partial) of chemical plant protection products. This underlines the necessity and relevance of creating a comprehensive software and mathematical tools for analyzing and predicting the dynamics of pest and entomophage populations, including allowing to consider possible economic effects.