Cost-effectiveness analysis: A tool in the hands of the clinician

De Carlo, Marco

doi:10.1177/2047487318822357

Cited by 1 publication

(2 citation statements)

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“…1,19 This analysis is a tool that can help in making health decisions, as well as focusing on other factors, such as patient expectations and ethical, cultural, and political concerns. 2 Additionally, it allows a clear understanding of the compensation between costs, harms, and benefits among treatments using a single metric. 1 The null hypothesis tested in this study was rejected, since the economic analysis showed that CP10 resulted in a higher cost-effectiveness ratio in both the Brazilian and American markets.…”

Section: Discussionmentioning

confidence: 99%

“…1 These analyses directly influence decision-making, along with efficacy, effectiveness, adverse effects, and longevity of the treatment protocol. 2 Tooth bleaching is one of the most common procedures requested by patients who are dissatisfied with their tooth color. However, the high cost of this treatment has stimulated the marketing of overthe-counter (OTC) products for at-home bleaching.…”

Section: Introductionmentioning

confidence: 99%

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At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysis

SANTOS,

SILVA,

CAVALCANTI

et al. 2024

J. Appl. Oral Sci.

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At-home bleaching versus whitening toothpastes for treatment of tooth discoloration: a cost-effectiveness analysisObjectives: This study aimed to analyze the cost-effectiveness of whitening toothpastes and at-home bleaching for the treatment of tooth discoloration.Methodology: A cost-effectiveness economic analysis was conducted, and eight randomized clinical trials were selected based on the whitening agent product used: blue covarine dentifrices (BCD), hydrogen peroxide dentifrices (HPD), dentifrices without bleaching agents (CD, negative control), and 10% carbamide peroxide (CP10, positive control) for at-home bleaching. The consumer/patient perspective was adopted, macro-costing techniques were used and a decision tree model was performed considering the costs in the American and Brazilian markets. The color change evaluation (ΔE* ab ) was used to calculate the effectiveness of tooth bleaching. A probabilistic analysis was performed using a Monte Carlo simulation and incremental cost-effectiveness ratios were obtained. Results: CP10 resulted in the highest cost-effectiveness compared to the use of dentifrices in both markets. In Brazil, HPD was more cost-effective than BCD and CD. In the US, the increased costs of HPD and BCD did not generate any whitening benefit compared to CD. Conclusions: CP10 was more cost-effective than BCD and HPD for tooth bleaching from the perspectives of the Brazilian and American markets. Decision-making should consider the use of CP10 for treating tooth discoloration.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%