2015
DOI: 10.1016/j.fertnstert.2015.02.012
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Cost-effectiveness analysis of preimplantation genetic screening and in vitro fertilization versus expectant management in patients with unexplained recurrent pregnancy loss

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Cited by 70 publications
(41 citation statements)
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“…12,13 The financial cost of a miscarriage was assumed to be US $1,300, US$600, US$200, and US$100 for high-, higher medium, lower medium, and low-cost scenario as previously reported. [14][15][16][17][18] All assumptions incorporated into this analysis included direct medical costs only, as indirect costs are highly variable and difficult to calculate. Costs for a previous diagnostic work-up before treatment were not included but assumed to be equal.…”
Section: Ivf Cost Scenariosmentioning
confidence: 99%
See 1 more Smart Citation
“…12,13 The financial cost of a miscarriage was assumed to be US $1,300, US$600, US$200, and US$100 for high-, higher medium, lower medium, and low-cost scenario as previously reported. [14][15][16][17][18] All assumptions incorporated into this analysis included direct medical costs only, as indirect costs are highly variable and difficult to calculate. Costs for a previous diagnostic work-up before treatment were not included but assumed to be equal.…”
Section: Ivf Cost Scenariosmentioning
confidence: 99%
“…A one-way sensitivity analysis investigated PGT-A cost scenarios ranging from US$1,000 to 10,000 in intervals of US$250, reflecting the great variations of international PGT-A costs. 16 Threshold analysis and incremental costeffectiveness ratio A threshold analysis for the maximum cost of PGT-A which would still provide cost-effectiveness was conducted for all scenarios. The theoretical necessary threshold for the clinical pregnancy rate to achieve cost-effectiveness of PGT-A was also estimated.…”
Section: Cost For Pgt-amentioning
confidence: 99%
“…Three studies have evaluated the cost‐effectiveness of PGT‐A version 2. Murugappan et al, applying PGT‐A to patients with unexplained recurrent miscarriages compared to expectant management, showed that PGT‐A could decrease abortion rate while live birth rate was not improved. Results of the analysis of the costs per live birth showed that IVF/PGT‐A was 100‐fold more expensive and consequently was not cost‐effective in increasing live birth.…”
Section: Threatsmentioning
confidence: 99%
“…PGT-A is the technique to select euploid embryos with the best implantation potential. This technique has been applied to treat patients with an increased risk of having aneuploid embryos, such as those with advanced maternal age 1,23 , repeated implantation failure 24 , and recurrent miscarriage [25][26][27] . Up to date, PGT-A studies remain limited and have not been reported for the clinical outcomes in patients with advanced maternal age in Vietnam.…”
Section: Introductionmentioning
confidence: 99%