Cost-Effectiveness of Current and Emerging Treatments of Varicose Veins

Epstein, David; Onida, Sarah; Bootun, Roshan; Ortega-Ortega, Marta; Davies, Alun H.

doi:10.1016/j.jval.2018.01.012

Cited by 47 publications

(56 citation statements)

References 63 publications

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“…The others are competing interventional therapies. The input data to the model are stylized but are intended to be fairly realistic (Epstein, Onida, Bootun, Ortega‐Ortega, & Davies, ), see Table S1.…”

Section: Methodsmentioning

confidence: 99%

Beyond the cost‐effectiveness acceptability curve: The appropriateness of rank probabilities for presenting the results of economic evaluation in multiple technology appraisal

Epstein

2019

Health Economics

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The cost‐effectiveness acceptability curve (CEAC) shows the probability that an option ranks first for net benefit. Where more than two options are under consideration, the CEAC offers only a partial picture of the decision uncertainty. This paper discusses the appropriateness of showing the full set of rank probabilities for reporting the results of economic evaluation in multiple technology appraisal (MTA). A case study is used to illustrate the calculation of rank probabilities and associated metrics, based on Monte Carlo simulations from a decision model. Rank probabilities are often used to show uncertainty in the results of network meta‐analysis, but until now have not been used for economic evaluation. They may be useful decision‐making tools to complement the CEAC in specific MTA contexts.

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Section: Methodsmentioning

confidence: 99%

Beyond the cost‐effectiveness acceptability curve: The appropriateness of rank probabilities for presenting the results of economic evaluation in multiple technology appraisal

Epstein

2019

Health Economics

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“…Esse desequilíbrio pode ser congênito ou adquirido, podendo atingir os sistemas venosos superficiais e profundos. A hipertensão do sistema venoso é a responsável pelo surgimento dos sintomas clínicos dessa enfermidade (4) .…”

Section: Introductionunclassified

“…Estudos apontam que a IVC pode causar tanto prejuízos funcionais no individuo quanto também afetar a sua qualidade de vida, decorrente de seus sinais vitais e sintomas, tais como: dor, edema, lipodermatoesclerose e dificuldade para caminhar e realizar atividades diárias de vida (3)(4)(5) .…”

Section: Introductionunclassified

Prevalência clínica-epidemiológica dos pacientes cirúrgicos de varizes em membros inferiores

Lucas

Seabra

Santos

et al. 2019

R. Enferm. Cent. O. Min.

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Objetivo: investigar a prevalência clínica-epidemiológica dos pacientes submetidos à cirurgia de varizes dos membros inferiores. Método: estudo prospectivo e transversal. Aplicou-se um questionário de qualidade de vida semiestruturado adaptado do Venous Insufficiency Epidemiological and Economic Study previamente à cirurgia e após 40 dias da cirurgia. Utilizou-se Teste de Qui-quadrado de Pearson para o valor esperado >5 e teste exato de Fisher para o valor

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“…Variköz venlerin bildirilen insidansı toplam popülasyonun %20 ila %64'ü arasında değişmektedir. Variköz venlerle ilişkili birçok durumda bulunan kalıntı varis oluşumları, yetişkinlerin %80'ine kadarında bulunabilir (8). Varisli damarlar (BSV ve dallarının yetersizliği), hastalar ve sağlık hizmetleri için önemli bir yük oluştururlar.…”

Section: Introductionunclassified

“…Batı ülkelerinin çoğunda toplam sağlık harcamalarının %3'ünü venöz hastalıklar oluşturur (9). Varisli damarlar için tedavi, hastalara sağlıkla ilgili yaşam kalitesinde önemli iyileşmeler sağlayabilir (8)…”

Section: Introductionunclassified

Mid and Long Term Results in Patients with Endovenous Radiofrequancy Ablation in Lower Extremity Venous Insufficiency

Kuserli¹,

Kavala²,

Türkyilmaz³

et al. 2019

BTDMJB

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Objective: Lower extremity venous insufficiency is a condition in which the flow of venous blood returns to the heart and the normal one-way rotation of the venous blood is reversed. As an alternative to open surgery in varicose veins, non-surgical endovascular procedures and hybrid endovascular procedures have emerged in the last decade. In this study, we aimed to evaluate the mid and long term results of endovenous radiofrequency ablation (RF) as an endovascular method. Methods: Between March 2015 and January 2017, 150 patients who underwent RF with the diagnosis of venous insufficiency were included in our study. 82 patients were female (54.7%), 68 were male (45.3%). The age range was 21-68 years old. Spinal anesthesia was performed in 139 patients and general anesthesia was performed in 11 patients. The RF ablation catheter was inserted into the Great Saphenous Vein (GSV) under the guidance of Doppler USG guided at the appropriate level below the knee. RF ablation was performed after approximately 1 cm distal of the superficial epigastric vein and then a flabectomy was performed. Result: Postoperative 1st 10th day, 1st 6th month and 1st 2nd year controls were performed. In control Doppler USG performed in sixth month, 135 patients (%90) had BSV complete occlusion and in 15 patients (%10) 40% recanalization. Six patients had deep venous insufficiency and 1 patient had perforating venous insufficiency. This patient developed varicose vein stockings in the medial malleolus and venous ulceration (C6) despite intensive medical therapy. Doppler USG performed in the first year of follow-up was 134 patients with GSV full occlusion and 16 patients with 40% recanalization. In the 2 year follow-up, there was no difference in the GSV patency rate between the first year and Doppler USG controls. Conclusion: We evaluated the mid and long term results of radiofrequency ablation in a single center, retrospectively in the treatment of venous insufficiency and varicose veins, which are common in the community. When applied with appropriate indication, radiofrequency ablation success rate is high, complication rate is low and it is also successful in terms of cosmetic results.

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Cost-Effectiveness of Current and Emerging Treatments of Varicose Veins

Cited by 47 publications

References 63 publications

Beyond the cost‐effectiveness acceptability curve: The appropriateness of rank probabilities for presenting the results of economic evaluation in multiple technology appraisal

Beyond the cost‐effectiveness acceptability curve: The appropriateness of rank probabilities for presenting the results of economic evaluation in multiple technology appraisal

Prevalência clínica-epidemiológica dos pacientes cirúrgicos de varizes em membros inferiores

Mid and Long Term Results in Patients with Endovenous Radiofrequancy Ablation in Lower Extremity Venous Insufficiency

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