Cost Effectiveness of Drug Coated Balloon Versus Percutaneous Transluminal Balloon Angioplasty In The Treatment of Peripheral Arterial Disease In Lower Limbs In Brazil

Pepe, C.; Fahham, L.; Follador, Wilson; Valencia, J.; Orozco, J.J.

doi:10.1016/j.jval.2015.09.088

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Drug-coated balloons have been demonstrated superior effectiveness and similar safety for the treatment of femoropopliteal lesions in different cohorts. [8,9,12,13] Anti-inflammatory and anticoagulant drugs may induce excellent patency and decrease the low CD-TLR rates. Independent studies have proved that drug-coated balloons resulted in higher primary patency and lower rate of vessel thrombosis.…”

Section: Discussionmentioning

confidence: 99%

Comparison between paclitaxel-coated balloon and standard uncoated balloon in the treatment of femoropopliteal long lesions in diabetics

Wang

et al. 2019

Medicine

View full text Add to dashboard Cite

Atherosclerotic diseases may include femoropopliteal artery stenosis or occlusion. Percutaneous transluminal angioplasty (PTA) is an effective and minimally invasive treatment strategy for atherosclerotic femoropopliteal artery stenosis/occlusion disease. Balloon angioplasty is a widely used technique in the management of occlusive disease in almost all arterial segments. We enrolled 111 diabetics with long femoropopliteal lesions, among which 54 received PTA with paclitaxel-coated balloon (the Paclitaxel group), and 57 with standard balloon catheters (the Control group). The primary outcome was set as angiographic late lumen loss (LLL) within 6 months; the secondary angiographic outcome was binary restenosis. Clinical outcomes included Rutherford clarification, ankle-brachial index (ABI) and rate of clinically driven target lesion revascularization (TLR). Two groups had similar basal clinical features, angiographic and procedural characteristics. Compared to controls, the Paclitaxel group had a significantly lower 6-month LLL rate, 12-month binary restenosis rate, 12-month TLR, lower Rutherford grades at 3 and 6 months, and higher ABI at 3 months. For all factors which might influence outcomes, fasting blood glucose was negatively correlated with ABI; the blood urea nitrogen (BUN) was positively related with the Rutherford clarification grades. In addition, the coronary heart disease (CHD) and smoking histories were positively correlated with residual stenosis after treatment. Collectively, the paclitaxel-coated balloon angioplasty can yield more favorable angiographic and clinical outcomes than standard uncoated balloon angioplasty, even in the more challenging lesions (the long and occlusive femoropopliteal lesions) in diabetics, when it had a similar safety profile to the traditional balloon. Blood glucose, BUN, CHD, and smoking imply poor curative effects.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparison between paclitaxel-coated balloon and standard uncoated balloon in the treatment of femoropopliteal long lesions in diabetics

Wang

et al. 2019

Medicine

View full text Add to dashboard Cite

show abstract

Cost Effectiveness of Drug Coated Balloon Versus Percutaneous Transluminal Balloon Angioplasty In The Treatment of Peripheral Arterial Disease In Lower Limbs In Brazil

Cited by 1 publication

References 0 publications

Comparison between paclitaxel-coated balloon and standard uncoated balloon in the treatment of femoropopliteal long lesions in diabetics

Comparison between paclitaxel-coated balloon and standard uncoated balloon in the treatment of femoropopliteal long lesions in diabetics

Contact Info

Product

Resources

About