Cost-Effectiveness of Home Hemodialysis With Bedside Portable Dialysis Machine "DIMI" in the United Arab Emirates

Jha, Chandra Mauli

doi:10.7759/cureus.18549

Cited by 3 publications

(2 citation statements)

References 38 publications

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“…However, the limitation of a patient's lifestyle and frequent visits to dialysis facilities still bother patients greatly. Thus, home dialysis was developed and improved patient quality of life significantly [94,95].…”

Section: Wearable Artificial Kidneysmentioning

confidence: 99%

Artificial Kidney Engineering: The Development of Dialysis Membranes for Blood Purification

Tang

Tsai

Chen³

et al. 2022

Membranes

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The artificial kidney, one of the greatest medical inventions in the 20th century, has saved innumerable lives with end stage renal disease. Designs of artificial kidney evolved dramatically in decades of development. A hollow-fibered membrane with well controlled blood and dialysate flow became the major design of the modern artificial kidney. Although they have been well established to prolong patients’ lives, the modern blood purification system is still imperfect. Patient’s quality of life, complications, and lack of metabolic functions are shortcomings of current blood purification treatment. The direction of future artificial kidneys is toward miniaturization, better biocompatibility, and providing metabolic functions. Studies and trials of silicon nanopore membranes, tissue engineering for renal cell bioreactors, and dialysate regeneration are all under development to overcome the shortcomings of current artificial kidneys. With all these advancements, wearable or implantable artificial kidneys will be achievable.

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Section: Wearable Artificial Kidneysmentioning

confidence: 99%

Artificial Kidney Engineering: The Development of Dialysis Membranes for Blood Purification

Tang

Tsai

Chen³

et al. 2022

Membranes

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“…However, under certain conditions kidney function can deteriorate and cause kidney failure, even leading to end stage renal disease when the kidneys are no longer able to perform their function. At this stage, replacement treatments are essential to survive [3], [4], [5], [6]. Extrarenal replacement by dialysis is today a recognized and widely proven therapeutic modality for end-stage chronic renal disease (ESRD).…”

Section: Introductionmentioning

confidence: 99%

Comparison of the Impact of Conventional Hemodialysis and Hemodiafiltration Techniques on the Evolution of Certain Mineral Bone Parameters in Chronic Hemodialysis Patients

Slimani

Jhilal

Ahid

et al. 2022

Open Access Maced J Med Sci

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Objective: The aim of this study was to compare the impact of conventional hemodialysis (HDC) and hemodiafiltration (HDF) techniques on the evolution of the parameters of phosphocalcic metabolism in chronic hemodialysis patients. Methods: This is a retrospective, descriptive and analytical study carried out in the hemodialysis center of Agadir medico-surgical center during 2015. The total number of patients is 34, 18 were treated by HDC ie 52.9% of cases. Also, 16 patients underwent HDF, ie 47.1% of cases. With each of the 2 techniques, the following parameters were measured: To assess the PTH level, we performed 3 measurements. To evaluate calcium, phosphorus, albumine and CRP levels, 7 measurements were taken. The data were entered via Excel and analyzed through Jamovi 1.6.9 software. We used the Wilcoxon or the Mann-Whitney test for the means. The factors associated with the variation of the studied parameters were analyzed in univariate and multivariate analyzes using the binary logistic regression model. Results: Our population was made up of 41.2% women and 58.8% men. Their average age was 55 ± 11 years. Also, 82.3% of cases had a normal build, 11.7% were overweight and 6% were moderately obese. The distribution of patients according to the causal nephropathy of chronic renal insufficiency presented a predominance of diabetic nephropathy (32.3%) followed by vascular pathology in 10 patients (29.4%). There was no statistically significant difference in the evolution of the levels of the parameters studied (PTH, calcium, phosphorus, albumin and CRP levels) over time. Univariate analysis showed that only the initial nephropathy factors: other nephropathy-vascular nephropathy (p= 0.028; OR=0.060; IC95% [0.004-0.734]) and diabetic nephropathy-vascular nephropathy (p= 0.011; OR=0.050; IC95% [0.004-0.508]) were associated with the variation of the studied parameters. The same factors also emerge in the multivariate analysis: other nephropathy-vascular nephropathy (p= 0.034; OR=0.044; IC95% [0.002-0.791]) and diabetic nephropathy-vascular nephropathy (p= 0.009; OR=0.032; IC95% [0.002-0.429]). Conclusion: According to our results, it seems that there are no significant differences in the evolution of some mineral bone parameters studied with the HDC and HDF techniques.

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Review Study about Portable and Wearable Artificial Kidney Systems

Aljanabi,

Lafta

2024

NJES

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Kidney renal failure is a life-threatening disease in which one or both kidneys are not functioning normally. The only available treatment other than a kidney transplant is to start on dialysis sessions, whether it is peritoneal or Hemo-dialysis[1].For some patients, the dialysis procedure is an exhausting and sometimes expensive trip to the specialized dialysis centers since it must be done about three times a week, depending on the physician's decision depending on the glomerular filtration rate of the kidneys[2-4].Different researchers have made many attempts over the years to replace conventional dialysis machines with more accessible at-home dialysis systems to provide patients with comfortable treatment sessions at the time they want without the need to change their lifestyle to fit the dialysis center's schedule.A review of the critical methods utilized in the creation and application of a portable dialysis machine that resembles the traditional dialysis center devices was conducted using a number of prior studies (research conducted between 2009 and 2024); the goal of all studies was to create a device that consists of filtering system, detection system to ensure there is no blood leakage and all parameters are within the acceptable limits, alarm system, and dialysate regeneration system, and each method will be described precisely in this review.As a result, the discussed studies found that using peristaltic pump pumps with a phase difference by half cycle between blood and dialysate will cause a higher urea clearance rate; multiple studies focused on the modification of the dialyzing filter to find that using Polyethene glycol surface-modified silicon nanopore membranes, dual-layer hollow fiber membranes, the use of BRECS cell therapy, carbon activated blocks, all contributed highly in enhancing the dialyzing process providing the patients with highly efficient blood purification session.

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Cost-Effectiveness of Home Hemodialysis With Bedside Portable Dialysis Machine "DIMI" in the United Arab Emirates

Cited by 3 publications

References 38 publications

Artificial Kidney Engineering: The Development of Dialysis Membranes for Blood Purification

Artificial Kidney Engineering: The Development of Dialysis Membranes for Blood Purification

Comparison of the Impact of Conventional Hemodialysis and Hemodiafiltration Techniques on the Evolution of Certain Mineral Bone Parameters in Chronic Hemodialysis Patients

Review Study about Portable and Wearable Artificial Kidney Systems

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