2017
DOI: 10.1371/journal.pone.0183391
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Cost-effectiveness of inactivated seasonal influenza vaccination in a cohort of Thai children ≤60 months of age

Abstract: BackgroundVaccination is the best measure to prevent influenza. We conducted a cost-effectiveness evaluation of trivalent inactivated seasonal influenza vaccination, compared to no vaccination, in children ≤60 months of age participating in a prospective cohort study in Bangkok, Thailand.MethodsA static decision tree model was constructed to simulate the population of children in the cohort. Proportions of children with laboratory-confirmed influenza were derived from children followed weekly. The societal per… Show more

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Cited by 7 publications
(13 citation statements)
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“…Total costs were not disaggregated in 4 studies (36%). 21,[23][24][25] Discounting of the costs was not performed in 7 studies (64%) but this was acceptable because discounting is not necessary when a study period is short. Nine studies (82%) had no sensitivity analysis of cost estimation; however, this was defensible as their study designs did not have assumptions on cost estimation or different cost scenarios.…”
Section: Resultsmentioning
confidence: 99%
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“…Total costs were not disaggregated in 4 studies (36%). 21,[23][24][25] Discounting of the costs was not performed in 7 studies (64%) but this was acceptable because discounting is not necessary when a study period is short. Nine studies (82%) had no sensitivity analysis of cost estimation; however, this was defensible as their study designs did not have assumptions on cost estimation or different cost scenarios.…”
Section: Resultsmentioning
confidence: 99%
“…Briefly, most studies had funding by non-profit organizations and employed a survey and/or hospital database for their cost estimation. Those 11 articles evaluated economic burden of influenza in the 3 main population groups: a) children, [23][24][25] b) older adults, 20,21,26 and c) individuals across various age groups/country. 6,14,22,27,28 Types of influenza illness varied across the studies: (i) influenza-like illness (ILI) which is considered a mild spectrum of influenza, (ii) seasonal influenza, (iii) influenza-associated acute respiratory illness or febrile respiratory illness, (iv) influenza-associated pneumonia, (v) avian influenza (H5N1), and (vi) the 2009 (H1N1) influenza pandemic.…”
Section: Resultsmentioning
confidence: 99%
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“…Enrollment method and study procedures have been previously described (Kittikraisak et al, 2018;Kittikraisak et al, 2017). Briefly, a prospective cohort study (Pediatric Respiratory Infection Cohort Evaluation, the PRICE study) to determine influenza burden among children living in the Bangkok Metropolitan areas who sought care at QSNICH (for any cause except acute respiratory illness) was established in August 2011.…”
Section: Enrollment Methods and Study Proceduresmentioning
confidence: 99%