2015
DOI: 10.1186/s12936-015-0696-1
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Cost-effectiveness of malaria diagnosis using rapid diagnostic tests compared to microscopy or clinical symptoms alone in Afghanistan

Abstract: Background: Improving access to parasitological diagnosis of malaria is a central strategy for control and elimination of the disease. Malaria rapid diagnostic tests (RDTs) are relatively easy to perform and could be used in primary level clinics to increase coverage of diagnostics and improve treatment of malaria. Methods: A cost-effectiveness analysis was undertaken of RDT-based diagnosis in public health sector facilities in Afghanistan comparing the societal and health sector costs of RDTs versus microscop… Show more

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Cited by 36 publications
(45 citation statements)
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“…These types of messages may attract more interest and willingness to engage among users. For example, compared with microscopy, RDT diagnosis of malaria in patients with uncomplicated febrile illness has high effectiveness and low cost [55]. How-to-use steps for RDT and how to read the results were shown in photographs.…”
Section: Discussionmentioning
confidence: 99%
“…These types of messages may attract more interest and willingness to engage among users. For example, compared with microscopy, RDT diagnosis of malaria in patients with uncomplicated febrile illness has high effectiveness and low cost [55]. How-to-use steps for RDT and how to read the results were shown in photographs.…”
Section: Discussionmentioning
confidence: 99%
“…The cost of RDTs has been declining over time46 with pan-specific tests available in the range of 1–2 U.S. Dollars (USD) 27. The cost-effectiveness studies that were surveyed used different costs and different measures of effectiveness such as “correctly treated” or “adequately diagnosed.” Two studies from different settings found RDTs to be a more cost-effectiveness option for diagnosis and treatment than microscopy (Table 1).…”
Section: Costs and Cost-effectiveness Of Diagnosis And Treatmentmentioning
confidence: 99%
“…The cost-effectiveness studies that were surveyed used different costs and different measures of effectiveness such as “correctly treated” or “adequately diagnosed.” Two studies from different settings found RDTs to be a more cost-effectiveness option for diagnosis and treatment than microscopy (Table 1). 20,27 In general, the cost-effectiveness of options for diagnosing P. vivax infections will depend on a number of factors including P. vivax prevalence, the operational accuracy of the different options (including presumptive and microscopy), cost of treatment, and provider adherence to the test result 20,27. A particularly important factor is the volume of patients: in a busy health center or hospital, microscopy may be very cost-effective per diagnosis, although there may be a trade-off in the time taken for diagnosis.…”
Section: Costs and Cost-effectiveness Of Diagnosis And Treatmentmentioning
confidence: 99%
“…This approach leads to very high levels of overprescription of antimalarials with > 99% of malaria-negative fever patients being incorrectly treated with an antimalarial drug in very low endemic areas of northern Afghanistan 2. RDTs have been demonstrated to have advantages over both clinical diagnosis and microscopy,11,12 although both microscopy and RDTs suffer from low sensitivity and can lead to species misclassification 13. RDTs have also demonstrated utility when deployed at community level though the large network of community health workers in the country.…”
Section: Diagnosis and Treatment Of Malariamentioning
confidence: 99%