Purpose: Percutaneous transforaminal endoscopy has been widely used to treat lumbar disc herniation, but the steep learning curve and difficulties in removing the calcified disc hinders the application of conventional endoscopy in treating calcified lumbar disc herniation. In 2017, we first reported Percutaneous Transforaminal Endoscopic Surgery (PTES) as an easy-to-learn posterolateral transforaminal endoscopic technique to decompress the nerve root for lumbar disc herniation. We used our PTES technique to remove the calcified lumbar disc herniation and the purpose of this study is to evaluate the safety and efficacy of this technique.Methods: Forty-six patients with calcified lumbar disc herniation (CLDH) and fifty-five patients with uncalcified lumbar disc herniation (ULDH) underwent PTES surgery to decompress the nerve root. Visual analogue scale was collected before the surgery, immediately, one week, one month, two months, three months, six months, 12 months and 24 months after surgery. The outcomes of MacNab classification were collected 24 months after surgery. Intra- and Post-operative complications were also recorded.Results: For CLDH patients, the VAS score was 9 (5-10) before operation, and then dropped to 2 (1-4) after surgery. VAS score continually decreased to 0 (0-3) at 24 months after surgery. 95.65% of CLDH patients showed excellent or good outcomes. ULDH group showed similar MacNab classification (94.55%) and VAS changing curve. The therapeutic effect of PTES in treating calcified lumbar disc herniation was as good as that in treating uncalcified patients.Conclusion: PTES is an effective and safe method to treat calcified lumbar disc herniation.