2010
DOI: 10.1111/j.1537-2995.2010.02686.x
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Cost‐effectiveness of screening the US blood supply for Trypanosoma cruzi

Abstract: Selective T. cruzi screening generates nearly the same effectiveness as universal screening, but at a reduced cost. Outcomes and associated costs of Chagas disease take longer to materialize than the average life expectancy of transfusion recipients.

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Cited by 34 publications
(31 citation statements)
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References 34 publications
(48 reference statements)
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“…We found that screening based on personal risk assessment and residence-exposure history (ie, time lived in rural and/or infested areas) is advantageous for capturing high-risk individuals. Studies of blood donors in Canada and the US have found promising usefulness and operational feasibility of residence history questionnaires [26], [27], [40].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…We found that screening based on personal risk assessment and residence-exposure history (ie, time lived in rural and/or infested areas) is advantageous for capturing high-risk individuals. Studies of blood donors in Canada and the US have found promising usefulness and operational feasibility of residence history questionnaires [26], [27], [40].…”
Section: Discussionmentioning
confidence: 99%
“…Several cost-effectiveness studies of Chagas disease interventions have focused on devising optimal insecticide application and blood donor testing schemes [25], [26], [27], [28], but few have examined strategies for human serologic testing in endemic or epidemic areas. A study by Mott et al [29] indicated the potential for targeted screening around detected positive children under 5 years of age in a rural area of Brazil.…”
Section: Introductionmentioning
confidence: 99%
“…In addition, the risk of acquiring Chagas' disease through infected blood transfusion is becoming a problem even in areas of nonendemicity, such as the United States and Europe, and some cases have already been reported (18,23,32). Owing to the risk of transmission by blood transfusion and organ transplantation, most blood donations in the United States have routinely been screened in recent years (1). Nevertheless, in many developed countries, the blood supply is not yet regularly tested for anti-T. cruzi antibodies (18,32).…”
mentioning
confidence: 99%
“…Six studies evaluated on Chagas disease interventions (two vector control, two vaccine, one screening, one blood supply screening) (Agapova et al, 2010;Lee et al, 2010Lee et al, , 2012aSicuri et al, 2011;Vazquez-Prokopec et al, 2009;Wilson et al, 2005). Studies found the interventions evaluated were cost-effective in Chagas endemic areas.…”
Section: Chagas Diseasementioning
confidence: 96%
“…Chagas is a public health concern even in nonendemic countries and is a growing problem due to migration and transmission through blood derivatives, organ transplant and through vertical transmission. One study modelled different screening methods of the U.S. blood supply though surveillance of various target groups (including testing donors from endemic countries) and will not be discussed in detail (Agapova et al, 2010). The other focussed on screening pregnant women from Latin America in nonendemic areas, with subsequent screening of newborns if positive (vertical transmission) (Sicuri et al, 2011).…”
Section: Chagas Diseasementioning
confidence: 99%