Cost effectiveness of strategies to combat breast, cervical, and colorectal cancer in sub-Saharan Africa and South East Asia: mathematical modelling study

Ginsberg, Gary; Lauer, Jeremy A.; Zelle, Sten G.; Baeten, Steef; Baltussen, Rob

doi:10.1136/bmj.e614

Cited by 122 publications

(121 citation statements)

References 38 publications

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“…It is suggested annual mammograms initial at age 40 and continuing for until a woman is healthy. Breast self-examination is still suggested as a common approach to rising breast awareness and therefore potentially allow for early detection for women in 20s although it has not been shown to be effective in reducing mortality (Ginsberg 2012;Andreeva, 2013). It is good women know how to check their breasts and report any breast problems quickly to their doctor.…”

Section: Introductionmentioning

confidence: 99%

Perception of Breast Cancer Screening among Iranian Women without Experience of Mammography: A Qualitative Study

Khazaee-Pool

Majlessi²,

Foroushani³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Background: In Iran, there are high rates of breast cancer. It is among the five most common cancers, the first among cancers diagnosed, and is the leading cause of cancer deaths among Iranian women. Objectives: The purpose of this qualitative study was to explore perception of breast cancer screening among Iranian women who have never had a mammograph. Materials and Methods: The current study was part of a qualitative research conducted by means of content analysis method and purposive sampling of 16 women over the age of 30 years who had not undergone mammography using individual semi-structured interviews. Interviews were recorded and transcribed verbatim. The data were under continuous consideration and comparative analysis in order to achieve data saturation. Results: After codification of data, three concept categories were achieved including: i) low awareness, ii) worries, and iii) lack of motivation. Conclusions: Although there is a tendency among Iranian women to participate in breast cancer screening, there is a powerful cultural belief that breasts are sexual organs that should not be discussed publicly. Due to the incidence of breast cancer in Iranian women, it is critical that breast awareness education be performed by health care experts to explore the concepts of breast cancer and breast cancer screening.

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Section: Introductionmentioning

confidence: 99%

Perception of Breast Cancer Screening among Iranian Women without Experience of Mammography: A Qualitative Study

Khazaee-Pool

Majlessi²,

Foroushani³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…BSE is a simple exercise which can potentially save the life of a woman. It is recommended for every woman above the age of 20 years to be done for 20 minutes every month (Ginseng et al, 2012). However, women in developing countries do not perform BSE for various reasons (Fung, 1998).…”

Section: Introductionmentioning

confidence: 99%

“…BSE is still recommended as a general approach to increasing breast health awareness and thus potentially allow for early detection of any anomalies, because it is free, painless and easy to practice (Ginseng et al, 2012). The American Cancer Society also recommends that women, starting from the age of 20 years should be educated on the pros and cons of performing a monthly BSE (The American Cancer Society, 2014).…”

Section: Introductionmentioning

confidence: 99%

Assessment of breast self-examination practice and associated factors among female health professionals in Western Ethiopia: A cross sectional study

Negeri¹,

Heyi²,

Melka³

2017

Int. J. Med. Med. Sci.

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Breast cancer is the leading cause of cancer mortality worldwide. Breast cancer incidence is increasing both in developed and developing regions. Regular breast self-examination (BSE) is one of the most cost effective methods for early detection of breast cancer in asymptomatic women. The aim of this study is to assess the magnitude of BSE practice and its associated factors among female health professionals working in public health facilities in Western Ethiopia. The study applied is health facility based cross-sectional study design. Simple random sampling technique was used to recruit a total of 390 female health professionals. The study was conducted from January to March, 2015. Bivariate and multivariable logistic regression model was used, odds ratios with 95% confidence intervals were computed and significance of all tests was decided at p-value of 0.05. From the total respondents, 77% had ever practiced BSE and only one third (33.7%) of them practiced regularly. Not experiencing breast problem (12.7%) was the main reason for not practicing regular BSE. After adjusting for possible confounders; personal history of breast cancer (AOR=4.7, 95%CI: 1.32-17.07), having knowledge of BSE (AOR=4.1, 95%CI: 1.36-5.65), positive attitude (AOR, 3.8, 95%CI: 2.10-9.17) and ever taught BSE to a client (AOR=5.2, 95%CI: 2.35-8.14) were found to be statistically significant predictors of BSE. Even though the life time BSE practice in this study was high, the regular BSE practice was low. Thus, trainings on BSE practice will be important to improve the practice level of health professionals and their counseling skill for the clients.

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“…Cervical cancer is the third most prevalent malignancy in women worldwide, and is a predominant cause of cancer-associated mortality in women in developing countries; with an estimated 527,600 novel cases and 265,700 mortalities worldwide in 2012 (1)(2)(3)(4)(5). In addition, cervical cancer accounts for 45% of the total number of cancer incidence in the south of China (6).…”

Section: Introductionmentioning

confidence: 99%

Association between the p73 gene G4C14-to-A4T14 single nucleotide polymorphism and risk of cervical cancer by high resolution melting and PCR with confronting two-pair primers in a Chinese population

Guo

Yang

et al. 2016

Oncology Letters

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Abstract. As a member of the p53 gene family, the p73 gene can affect an individual's susceptibility to cancer through a p53-like manner. DNA sequence variation in the p73 gene has been reported to be associated with cancer risk. The present study aimed to identify whether the p73 gene G4C14-to-A4T14 single nucleotide polymorphism (SNP) is associated with risk of cervical cancer in a Chinese population. The p73 G4C14-to-A4T14 polymorphism was genotyped in 175 cervical cancer and 189 healthy control peripheral blood DNA samples using high resolution melting, polymerase chain reaction with confronting two-pair primers and direct DNA sequencing. The results demonstrated that carriers of the AT/AT genotype were associated with a significantly increased risk of cervical cancer (P=0.042; χ 2 =4.122; odds ratio = 2.241; 95% confidence interval = 1.013-4.956) compared with the GC/GC genotype carriers. In addition, there was a significant association between p73 genotypes and tumor size in patients with cervical cancer (P=0.014; χ 2 =8.607). However, no association was identified between p73 genotypes and tumor stage, histological type or lymph node metastasis in patients with cervical cancer. These results suggest that the p73 G4C14-to-A4T14 SNP may function as a marker of genetic susceptibility to cervical cancer in the Chinese population.

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Cost effectiveness of strategies to combat breast, cervical, and colorectal cancer in sub-Saharan Africa and South East Asia: mathematical modelling study

Cited by 122 publications

References 38 publications

Perception of Breast Cancer Screening among Iranian Women without Experience of Mammography: A Qualitative Study

Perception of Breast Cancer Screening among Iranian Women without Experience of Mammography: A Qualitative Study

Assessment of breast self-examination practice and associated factors among female health professionals in Western Ethiopia: A cross sectional study

Association between the p73 gene G4C14-to-A4T14 single nucleotide polymorphism and risk of cervical cancer by high resolution melting and PCR with confronting two-pair primers in a Chinese population

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