This paper describes one approach to a methodology to design reinforced concrete cantilever retaining walls for road construction, using a hybrid multistart optimization strategic method based on a variable neighborhood search threshold acceptance strategy (VNS-MTAR) algorithm. This algorithm is applied to two objective functions: the embedded CO2 emissions and the economic cost of reinforced concrete walls at different stages of materials production, transportation and construction. The problem involved 20 design variables: four geometric variables (thickness of the stem and the base slab, as well as the toe and heel lengths), four material types, and 12 variables for the reinforcement set-up. Results first indicate that embedded emissions and cost are closely related, and that more environmentally-friendly solutions than the lowest cost solution are available at a cost increment of less than 1.28%. The analysis also indicated that reducing costs by one euro could save up to 2.28% kg in CO2 emissions.Finally, the cost-optimized walls require about 4.8% more concrete than the best environmental ones, which need 1.9% more steel.