Cost-utility of a guided Internet-based intervention in comparison with attention only for people with HIV and depressive symptoms: A randomized controlled trial

Luenen, Sanne van; Garnefski, Nadia; Spinhoven, Philip; Marle, M. van den Akker – van Elske

doi:10.1016/j.jpsychores.2019.01.012

Cited by 7 publications

(9 citation statements)

References 34 publications

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“…Four guided [53][54][55][56] IMIs, compared with WLC, were considered cost-effective (<£30,000 per QALY gained, probabilities ranging from 55 53 to 98% 55 ) from the societal and healthcare perspective. Results of the cost-effectiveness analyses were unclear 54 or showed a low likelihood of being cost-effective at a WTP of nil from a societal perspective (CEA = 30-38% 53 ).…”

Section: Mddmentioning

confidence: 99%

Systematic review of economic evaluations for internet- and mobile-based interventions for mental health problems

et al. 2022

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In view of the staggering disease and economic burden of mental disorders, internet and mobile-based interventions (IMIs) targeting mental disorders have often been touted to be cost-effective; however, available evidence is inconclusive and outdated. This review aimed to provide an overview of the cost-effectiveness of IMIs for mental disorders and symptoms. A systematic search was conducted for trial-based economic evaluations published before 10th May 2021. Electronic databases (including MEDLINE, PsycINFO, CENTRAL, PSYNDEX, and NHS Economic Evaluations Database) were searched for randomized controlled trials examining IMIs targeting mental disorders and symptoms and conducting a full health economic evaluation. Methodological quality and risk of bias were assessed. Cost-effectiveness was assumed at or below £30,000 per quality-adjusted life year gained. Of the 4044 studies, 36 economic evaluations were reviewed. Guided IMIs were likely to be cost-effective in depression and anxiety. The quality of most evaluations was good, albeit with some risks of bias. Heterogeneity across studies was high because of factors such as different costing methods, design, comparison groups, and outcomes used. IMIs for anxiety and depression have potential to be cost-effective. However, more research is needed into unguided (preventive) IMIs with active control conditions (e.g., treatment as usual) and longer time horizon across a wider range of disorders.Trial registration: PROSPERO Registration No. CRD42018093808.

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Section: Mddmentioning

confidence: 99%

Systematic review of economic evaluations for internet- and mobile-based interventions for mental health problems

et al. 2022

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“…Only three out of the 29 studies explicitly reported to have undertaken a CUA [ 35 – 37 ] and one study was explicit about having conducted both a CEA and CUA [ 38 ]. Modelling was used in all but two studies, which were trial-based [ 36 , 37 ]. Most of the modelling studies applied a (dynamic) transmission model, which is the preferred method when evaluating infectious diseases [ 39 – 47 ].…”

Section: Resultsmentioning

confidence: 99%

“…Vaccination and screening interventions dominated, and involved stand-alone vaccination [ 45 , 50 – 52 ], vaccination in addition to screening [ 40 , 53 – 56 ], vaccination of girls and boys [ 43 , 47 ], sex-neutral vaccination [ 49 ], screening (stand-alone) [ 41 , 57 – 59 ], screening in addition to testing [ 60 ] and screening after vaccination [ 61 ]. Other interventions involved test and treat interventions including PrEP (Pre-Exposure Prophylaxis) [ 42 , 62 ], testing and linkage to care [ 37 ] and opt-out testing strategy [ 46 ]; expedited partner treatment [ 46 ], population-level treatment expansion [ 44 ], (on-demand) PrEP [ 35 , 63 ], treatment adherence interventions [ 38 ], guided internet-based behaviour intervention [ 36 ] and financial incentives [ 39 ].…”

Section: Resultsmentioning

confidence: 99%

“…Here, productivity was attributable to the HIV-related morbidity and mortality and lost income due to death or disability from hepatitis B-related sequelae, both chronic conditions. Presenteeism was only accounted for by two studies [ 36 , 58 ]. Few studies estimated lost income [ 39 , 51 ], lost revenue due to unemployment rate gap [ 63 ], fringe benefits [ 39 ], early retirement [ 58 ], avoided future production loss (in a sensitivity analysis) [ 62 ] and intervention-related productivity gains [ 44 , 51 ].…”

Section: Resultsmentioning

confidence: 99%

“…Only four studies explicitly reported capturing the costs associated with non-paid work (i.e. domestic tasks, voluntary work) [ 36 , 38 , 39 , 52 ]. It was not clear if/how many studies equated non-paid opportunity costs (i.e.…”

Section: Resultsmentioning

confidence: 99%

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Are intersectoral costs considered in economic evaluations of interventions relating to sexually transmitted infections (STIs)? A systematic review

et al. 2022

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Background/objective Sexually transmitted infections (STIs) not only have an impact on the health sector but also the private resources of those affected, their families and other sectors of society (i.e. labour, education). This study aimed to i) review and identify economic evaluations of interventions relating to STIs, which aimed to include a societal perspective; ii) analyse the intersectoral costs (i.e. costs broader than healthcare) included; iii) categorise these costs by sector; and iv) assess the impact of intersectoral costs on the overall study results. Methods Seven databases were searched: MEDLINE (PubMed), EMBASE (Ovid), Web of Science, CINAHL, PsycINFO, EconLit and NHS EED. Key search terms included terms for economic evaluation, STIs and specific infections. This review considered trial- and model-based economic evaluations conducted in an OECD member country. Studies were included that assessed intersectoral costs. Intersectoral costs were extracted and categorised by sector using Drummond’s cost classification scheme (i.e. patient/family, productivity, costs in other sectors). A narrative synthesis was performed. Results Twenty-nine studies qualified for data extraction and narrative synthesis. Twenty-eight studies applied a societal perspective of which 8 additionally adopted a healthcare or payer perspective, or both. One study used a modified payer perspective. The following sectors were identified: patient/family, informal care, paid labour (productivity), non-paid opportunity costs, education, and consumption. Patient/family costs were captured in 11 studies and included patient time, travel expenses, out-of-pocket costs and premature burial costs. Informal caregiver support (non-family) and unpaid help by family/friends was captured in three studies. Paid labour losses were assessed in all but three studies. Three studies also captured the costs and inability to perform non-paid work. Educational costs and future non-health consumption costs were each captured in one study. The inclusion of intersectoral costs resulted in more favourable cost estimates. Conclusions This systematic review suggests that economic evaluations of interventions relating to STIs that adopt a societal perspective tend to be limited in scope. There is an urgent need for economic evaluations to be more comprehensive in order to allow policy/decision-makers to make better-informed decisions.

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Economic Evaluations of Internet-Based Psychological Interventions for Anxiety Disorders and Depression: A Systematic Review

Mitchell

Joshi

Patel

et al. 2021

Journal of Affective Disorders

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Cost-utility of a guided Internet-based intervention in comparison with attention only for people with HIV and depressive symptoms: A randomized controlled trial

Abstract: van den Akker-van Marle , Cost-utility of a guided Internetbased intervention in comparison with attention only for people with HIV and depressive symptoms: A randomized controlled trial. Psr (2019),

Cited by 7 publications

References 34 publications

Systematic review of economic evaluations for internet- and mobile-based interventions for mental health problems

Systematic review of economic evaluations for internet- and mobile-based interventions for mental health problems

Are intersectoral costs considered in economic evaluations of interventions relating to sexually transmitted infections (STIs)? A systematic review

Economic Evaluations of Internet-Based Psychological Interventions for Anxiety Disorders and Depression: A Systematic Review

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