Costi della gastroenterite da rotavirus acquisita in comunità in età pediatrica a Padova in Italia

Giaquinto, Carlo; Callegaro, Sara; Andreola, Barbara; Bernuzzi, Mauro; Cantarutti, Luigi; D'Elia, R; Drago, Sandro; Marchi, Antonella; Falconi, P; Felice, Maurilio De; Giancola, G.; Lista, C.; Manni, C.; Perin, M.; Pisetta, F.; Scamarcia, A; Sidran, M. P.; Largeron, Nathalie; Trichard, M; Dalt, Liviana Da

doi:10.1007/bf03320704

Cited by 7 publications

(7 citation statements)

References 22 publications

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“…The average cost of a day in hospital in an Italian pediatric ward is 434.58 Euro [39-41], while the average unitary cost of a lost day of work is 148.00 Euro [42,43]. …”

Section: Resultsmentioning

confidence: 99%

“…Based on the differences we found in our study in the length of hospital stay between the children affected and the ones not affected by NRVI, the total increase in hospital stay caused by NRVI can be estimated to be 13,764.9 days. The average cost of a day in hospital in an Italian pediatric ward is 434.58 Euro [ 39 - 41 ], while the average unitary cost of a lost day of work is 148.00 Euro [ 42 , 43 ].…”

Section: Resultsmentioning

confidence: 99%

“…- the cost of the days spent in hospital, based on the Diagnosis Related Groups [ 39 - 41 ] of the Italian Ministry of Health;…”

Section: Methodsmentioning

confidence: 99%

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Nosocomial Rotavirus Gastroenteritis in pediatric patients: a multi-center prospective cohort study

et al. 2010

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BackgroundFew data are available on the incidence of nosocomial Rotavirus infections (NRVI) in pediatric hospitals and on their economic impact. The goals of this study were: to evaluate the incidence of NRVI in various Italian pediatric wards during the course of two peak RV seasons; to investigate possible risk factors for NRVI; to estimate the costs caused by NRVI.Methodsprospective cohort study. Population: all the children under 30 months of age who were admitted without any symptom or diagnosis of gastroenteritis in the pediatric hospitals of Florence, Naples, Brescia and Ancona, Italy, during the winter-spring periods 2006-2007 and 2007-2008. Serial RV rapid tests and clinical monitoring were carried out on the cohort. Telephone interviews were performed from 3 to 5 days after discharge.Results520 out of 608 children completed the study (85.6%). The overall incidence of NRVI was 5.3% (CI95% 3.6-7.5), (7.9 per 1,000 days of hospital stay, CI 95% 5.3-11.3). The average duration of hospital stay was significantly longer for children who had NRVI (8.1 days, SD 5.4) than for non-infected children (6.4 days, SD 5.8, difference 1.7 days, p = 0.004). The risk of contracting NRVI increased significantly if the child stayed in hospital more than 5 days, RR = 2.8 (CI95% 1.3-6), p = 0.006. In Italy the costs caused by NRVI can be estimated at 8,019,155.44 Euro per year. 2.7% of the children hospitalized with no gastroenteritis symptoms tested positive for RV.ConclusionsOur study showed a relevant incidence of NRVI, which can increase the length of the children's stay in hospital. Limiting the number of nosocomial RV infections is important to improve patients' safety as well as to avoid additional health costs.

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“…The average cost of a day in hospital in an Italian pediatric ward is 434.58 Euro [39-41], while the average unitary cost of a lost day of work is 148.00 Euro [42,43]. …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Nosocomial Rotavirus Gastroenteritis in pediatric patients: a multi-center prospective cohort study

et al. 2010

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“…The burden of the medical costs for RVGE has been recently calculated for some European countries [4][5][6][7]. The results of the economic evaluations suggest that hospital admissions generate significant medical treatment costs throughout Europe.…”

Section: Introductionmentioning

confidence: 99%

An economic analysis of rotavirus vaccination in Italy

Giammanco

Coniglio

Pignato

et al. 2009

Vaccine

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“…The incidence rate of emergency care visits for RVGE was reported by only one study from Italy, with an incidence rate of 1890 per 100 000 children per year (95% CI: 1597-2207) [83].…”

Section: Emergency Care Visitsmentioning

confidence: 99%

Rotavirus disease and health care utilisation among children under 5 years of age in highly developed countries: a systematic review and meta-analysis

Ardura‐Garcia

Kreis

Rakic

et al. 2020

Preprint

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BackgroundRotavirus (RV) infection is the leading cause of diarrhoea-associated morbidity and mortality globally among children under 5 years of age. RV vaccination is available, but has not been implemented in many national immunisation plans, especially in highly developed countries. This systematic review aimed to estimate the prevalence and incidence of health care use for RV gastroenteritis (RVGE) among children aged under 5 years in highly developed countries without routine RV vaccination.MethodsWe searched MEDLINE and Embase databases from January 1st 2000 to December 17th 2018 for publications reporting on incidence or prevalence of RVGE-related health care use in children below 5 years of age: primary care and emergency department (ED) visits, hospitalisations, nosocomial infections and deaths. We included only studies with laboratory-confirmed RV infection, undertaken in highly developed countries with no RV routine vaccination plans. We used random effects meta-analysis to generate summary estimates with 95% confidence intervals (CI) and prediction intervals.ResultsWe screened 4033 abstracts and included 74 studies from 21 countries. Average incidence rates of RVGE per 100 000 person-years were: 2484 (95% CI 697-5366) primary care visits, 1890 (1597-2207) ED visits, 500 (422-584) hospitalisations, 34 (20-51) nosocomial infections and 0.04 (0.02-0.07) deaths. Average proportions of cases of acute gastroenteritis caused by RV were: 21% (95% CI 16-26%) for primary care visits; 32% (25-38%) for ED visits; 41% (36-47%) for hospitalisations, 29% (25-34%) for nosocomial infections and 12% (8-18%) for deaths. Results varied widely between and within countries, and heterogeneity was high (I2>90%) in most models.ConclusionRV in children under 5 years causes many healthcare visits and hospitalisations, with low mortality, in highly developed countries without routine RV vaccination. The health care use estimates for RVGE obtained by this study can be used to model RV vaccine cost-effectiveness in highly developed countries.Take home messageRV-caused illness leads to a high burden of health care usage in highly developed countries who have not introduced RV vaccination.

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Costi della gastroenterite da rotavirus acquisita in comunità in età pediatrica a Padova in Italia

Cited by 7 publications

References 22 publications

Nosocomial Rotavirus Gastroenteritis in pediatric patients: a multi-center prospective cohort study

Nosocomial Rotavirus Gastroenteritis in pediatric patients: a multi-center prospective cohort study

An economic analysis of rotavirus vaccination in Italy

Rotavirus disease and health care utilisation among children under 5 years of age in highly developed countries: a systematic review and meta-analysis

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