Costocondritis y espondilitis diferidas por Candida en paciente post-COVID-19 tratado previamente con corticoides, antibióticos y tocilizumab

Gorospe‐Sarasúa, Luis; Gallego-Rivera, José Ignacio; Muñoz-Molina, Gemma María; Mirambeaux-Villalona, Rosa Mariela; Ajuria-Illarramendi, Odile; González-García, Andrés; Barbolla-Díaz, Ignacio

doi:10.1016/j.arbres.2020.12.002

Cited by 5 publications

(3 citation statements)

References 13 publications

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“…There were 11 cases of candidemia due to C. auris: two strains in the study of Allaw et al and three in the study of De Almeida et al were resistant to fluconazole and amphotericin B [112,114]; all of the six strains reported by Villanueva were resistant to amphotericin B and three were resistant to fluconazole [119]. A secondary infectious focus was described in four patients (one had endophthalmitis, one retinitis, one endocarditis, and one had fungal costochondritis and spondylitis confirmed by bone biopsy histology and culture) [109,113,123]. Anti-fungal treatment was received by 87.8% of the patients, mainly echinocandins (86%).…”

Section: Case Reports and Case Seriesmentioning

confidence: 93%

“…Nine case reports and seven case series were retrieved [108][109][110][111][112][113][114][115][116][117][118][119][120][121][122][123], together reporting 41 cases of candidemia (Table 4; detailed information about the individual studies is given in Table S4). The median time from ICU admission or intubation to the diagnosis of candidemia was 13.5 days (IQR 7.5-29.5), and more than 80% of the patients had an indwelling vascular catheter, received broad-spectrum antibiotics, and underwent mechanical ventilation before its onset.…”

Section: Case Reports and Case Seriesmentioning

confidence: 99%

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Invasive Fungal Infections Complicating COVID-19: A Narrative Review

Casalini

Giacomelli

Ridolfo

et al. 2021

JoF

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Invasive fungal infections (IFIs) can complicate the clinical course of COVID-19 and are associated with a significant increase in mortality, especially in critically ill patients admitted to an intensive care unit (ICU). This narrative review concerns 4099 cases of IFIs in 58,784 COVID-19 patients involved in 168 studies. COVID-19-associated invasive pulmonary aspergillosis (CAPA) is a diagnostic challenge because its non-specific clinical/imaging features and the fact that the proposed clinically diagnostic algorithms do not really apply to COVID-19 patients. Forty-seven observational studies and 41 case reports have described a total of 478 CAPA cases that were mainly diagnosed on the basis of cultured respiratory specimens and/or biomarkers/molecular biology, usually without histopathological confirmation. Candidemia is a widely described secondary infection in critically ill patients undergoing prolonged hospitalisation, and the case reports and observational studies of 401 cases indicate high crude mortality rates of 56.1% and 74.8%, respectively. COVID-19 patients are often characterised by the presence of known risk factors for candidemia such as in-dwelling vascular catheters, mechanical ventilation, and broad-spectrum antibiotics. We also describe 3185 cases of mucormycosis (including 1549 cases of rhino-orbital mucormycosis (48.6%)), for which the main risk factor is a history of poorly controlled diabetes mellitus (>76%). Its diagnosis involves a histopathological examination of tissue biopsies, and its treatment requires anti-fungal therapy combined with aggressive surgical resection/debridement, but crude mortality rates are again high: 50.8% in case reports and 16% in observational studies. The presence of other secondary IFIs usually diagnosed in severely immunocompromised patients show that SARS-CoV-2 is capable of stunning the host immune system: 20 cases of Pneumocystis jirovecii pneumonia, 5 cases of cryptococcosis, 4 cases of histoplasmosis, 1 case of coccidioides infection, 1 case of pulmonary infection due to Fusarium spp., and 1 case of pulmonary infection due to Scedosporium.

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Section: Case Reports and Case Seriesmentioning

confidence: 93%

Section: Case Reports and Case Seriesmentioning

confidence: 99%

Invasive Fungal Infections Complicating COVID-19: A Narrative Review

Casalini

Giacomelli

Ridolfo

et al. 2021

JoF

View full text Add to dashboard Cite

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“…To the best of our knowledge, this is the first published case of post-COVID-19 Tietze’s syndrome in an adult who is otherwise immunocompetent. Previously, post-COVID-19 costochondritis was reported in adolescents and adults treated with immunosuppressants [ 9 - 10 ]. However, there is no literature surrounding post-COVID-19 costochondritis or Tietze’s syndrome in an individual who had not recently received immunosuppressants.…”

Section: Discussionmentioning

confidence: 99%

Tietze’s Syndrome Post-COVID-19 Infection in an Adult Patient

Tan¹,

Lim²,

Yeow³

et al. 2022

Cureus

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Tietze's syndrome is a rare inflammatory disorder characterized by chest well swelling and inflammation of the costal cartilages. We describe a gentleman with repeated presentations to the emergency department (ED) with left-sided chest and sternoclavicular pain on a background of recent asymptomatic coronavirus disease 2019 (COVID-19) infection. He had elevated inflammatory markers and MRI subsequently confirmed the diagnosis of Tietze's syndrome. Anti-inflammatory medications and colchicine eventually led to a complete resolution of symptoms. This case highlights how Tietze's syndrome --a disorder that is potentially self-limiting, can cause great distress and should be a differential diagnosis of chest pain after excluding life-threatening etiologies related to COVID-19.

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COVID-19 musculoskeletal involvement in children

Giraudo,

Fichera,

Pilati

et al. 2023

Front. Pediatr.

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Since the early phases of the COVID-19 pandemic, it has become clear that children are affected by mild respiratory symptoms rather than the critical pneumonia typical in adults. Nevertheless, it took longer to understand that pediatric patients with SARS-COV2 may develop a severe multisystem inflammatory response (a.k.a. multisystem inflammatory syndrome in children (MIS-C)), which can include musculoskeletal symptoms, and/or arthritis and myositis independently from MIS-C. Diagnostic imaging significantly contributed to the assessment of pulmonary disease due to COVID-19 but it has been rarely applied to evaluate musculoskeletal involvement in children with or without previous rheumatic diseases. Despite the paucity of radiological literature, muscle edema at magnetic resonance and synovitis at ultrasound have been described. Further use of diagnostic imaging for children with articular and muscular symptoms due to COVID-19 is strongly encouraged.

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Costocondritis y espondilitis diferidas por Candida en paciente post-COVID-19 tratado previamente con corticoides, antibióticos y tocilizumab

Cited by 5 publications

References 13 publications

Invasive Fungal Infections Complicating COVID-19: A Narrative Review

Invasive Fungal Infections Complicating COVID-19: A Narrative Review

Tietze’s Syndrome Post-COVID-19 Infection in an Adult Patient

COVID-19 musculoskeletal involvement in children

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