Costs, Charges, and Revenues for Hospital Diagnostic Imaging Procedures: Differences by Modality and Hospital Characteristics

Sistrom, Chris L.; McKay, Niccie L.

doi:10.1016/j.jacr.2004.09.013

Cited by 106 publications

(70 citation statements)

References 10 publications

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“…The list price of the FilmArray GI panel is $155 per test. Hospital stay costs were approximated to be $800 per day, and radiology costs were as follows: X-ray, $55; ultrasound, $55; CT scan, $51; and MRI, $165 (as published by Sistrom and McKay [4]). All costs listed were irrespective of patient charges or reimbursement.…”

Section: Methodsmentioning

confidence: 99%

A Gastrointestinal PCR Panel Improves Clinical Management and Lowers Health Care Costs

et al. 2018

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Conventional methods for the identification of gastrointestinal pathogens are time-consuming and expensive and have limited sensitivity. The aim of this study was to determine the clinical impact of a comprehensive molecular test, the BioFire FilmArray gastrointestinal (GI) panel, which tests for many of the most common agents of infectious diarrhea in approximately 1 h. Patients with stool cultures submitted were tested on the GI panel ( = 241) and were compared with control patients ( = 594) from the year prior. The most common organisms detected by the GI panel were enteropathogenic (EPEC, = 21), norovirus ( = 21), rotavirus ( = 15), sapovirus ( = 9), and ( = 8). Patients tested on the GI panel had an average of 0.58 other infectious stool tests compared with 3.02 in the control group ( = 0.0001). The numbers of days on antibiotic(s) per patient were 1.73 in the cases and 2.12 in the controls ( = 0.06). Patients with the GI panel had 0.18 abdomen and/or pelvic imaging studies per patient compared with 0.39 ( = 0.0002) in the controls. The average length of time from stool culture collection to discharge was 3.4 days in the GI panel group versus 3.9 days in the controls ( = 0.04). The overall health care cost could have decreased by $293.61 per patient tested. The GI panel improved patient care by rapidly identifying a broad range of pathogens which may not have otherwise been detected, reducing the need for other diagnostic tests, reducing unnecessary use of antibiotics, and leading to a reduction in hospital length of stay.

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Section: Methodsmentioning

confidence: 99%

A Gastrointestinal PCR Panel Improves Clinical Management and Lowers Health Care Costs

et al. 2018

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“…Ultrasound has the advantages of low cost, safety, and ease of operation compared to other imaging modalities, such as computed tomography, magnetic resonance imaging, and positron emission tomography. 19,20 In addition, US can provide real-time imaging while protecting patients from the risks of radiation. 21 Therefore, US is often used as one of the preferred methods for diagnosing, treating, and monitoring disease.…”

Section: Discussionmentioning

confidence: 99%

Optimized Anti–Prostate‐Specific Membrane Antigen Single‐Chain Variable Fragment–Loaded Nanobubbles as a Novel Targeted Ultrasound Contrast Agent for the Diagnosis of Prostate Cancer

Ding

Cao

Qian

et al. 2019

J of Ultrasound Medicine

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Objectives To prepare optimized prostate‐specific membrane antigen (PSMA) single‐chain variable fragment (scFv)–loaded nanobubbles (NBs) as a novel targeted ultrasound (US) contrast agent for diagnosis and treatment of prostate cancer (PCa). Methods Prostate‐specific membrane antigen scFv‐loaded NBs were prepared by membrane hydration and biotin‐streptavidin conjugation. Flow cytometry was used to observe the binding rate of the targeted NBs to PSMA‐expressing cells. Contrast‐enhanced US was used to monitor targeted and nontargeted NBs administered to nude mice with 22RV1, LNCaP, and PC‐3 xenograft tumors. The specific binding ability of the targeted NBs was further examined by fluorescence imaging of tumor cryosections. Results Uniformly sized targeted NBs were successfully prepared (mean ± SD, 485.3 ± 28.4 nm). The NBs showed good stability and bound specifically to LNCaP and 22RV1 cells with high PSMA expression in vitro but did not bind to PC‐3 cells without PSMA expression. The targeted NBs presented good US enhancement, and the results of the in vivo xenograft tumor nude mouse model showed that the peak contrast intensity in LNCaP and 22RV1 cells was significantly higher for the targeted NBs than the nontargeted NBs (P < .05), whereas there was no significant difference in PC‐3 cells. Immunofluorescence results obtained from tumor sections confirmed that the targeted NBs were capable of targeting PSMA‐expressing tumor cells. Conclusions These novel PSMA scFv‐loaded NBs have proven to be an excellent US contrast agent for imaging PSMA‐expressing PCa and have the potential to not only enable efficient and safe molecular imaging but also to serve as a delivery system for targeted PCa therapies.

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“…In our practice, we now routinely perform an MRI of the brain without contrast for all our patients in whom circulatory arrest is planned. A routine MRI of the brain without contrast results in no patient radiation exposure and the mean cost per patient is estimated to be $2048, 36 compared to the average cost of hospitalization for an ischemic stroke of $18, 963 ± $21 454. 37 In summary, WMIC may be a clinically important risk factor and clinical marker of patients at risk for postoperative stroke after thoracic aortic surgery.…”

Section: Discussionmentioning

confidence: 99%

Deep chronic microvascular white matter ischemic change as an independent predictor of acute brain infarction after thoracic aortic replacement

et al. 2018

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Costs, Charges, and Revenues for Hospital Diagnostic Imaging Procedures: Differences by Modality and Hospital Characteristics

Cited by 106 publications

References 10 publications

A Gastrointestinal PCR Panel Improves Clinical Management and Lowers Health Care Costs

A Gastrointestinal PCR Panel Improves Clinical Management and Lowers Health Care Costs

Optimized Anti–Prostate‐Specific Membrane Antigen Single‐Chain Variable Fragment–Loaded Nanobubbles as a Novel Targeted Ultrasound Contrast Agent for the Diagnosis of Prostate Cancer

Deep chronic microvascular white matter ischemic change as an independent predictor of acute brain infarction after thoracic aortic replacement

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