Cough in COPD

Smith, Jennifer A.; Owen, Emily; Earis, J. E.; Woodcock, Ashley

doi:10.1016/s0012-3692(15)51851-5

Cited by 34 publications

(7 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There has been literature published on the objective measures, such as airflow and subjective judgment of cough strength. The judgments on subjective cough strength can be provided through training by clinician or speech language therapist [22]. A reliable cough reflex test with a subjective strength rating may be more beneficial to clinical swallowing evaluation, and it can be used as bedside screening test.…”

Section: Discussionmentioning

confidence: 99%

Usefulness of the Simplified Cough Test in Evaluating Cough Reflex Sensitivity as a Screening Test for Silent Aspiration

et al. 2014

View full text Add to dashboard Cite

ObjectiveTo assess cough reflex sensitivity using the simplified cough test (SCT) and to evaluate the usefulness of SCT to screen for silent aspiration.MethodsThe healthy control group was divided into two subgroups: the young (n=29, 33.44±9.99 years) and the elderly (n=30, 63.66±4.37 years). The dysphagic elderly group (n=101, 72.95±9.19 years) consisted of patients with dysphagia, who suffered from a disease involving central nervous system (ischemic stroke 47, intracerebral hemorrhage 27, traumatic brain injury 11, encephalitis 5, hypoxic brain damage 3, and Parkinson disease 8). The SCT was performed using the mist of a 1% citric acid from a portable nebulizer. The time from the start of the inhalation to the first cough was measured as the cough latency. All the dysphagic patients underwent the videofluoroscopic swallowing study.ResultsThe cough latency was more significantly prolonged in the healthy elderly group than in the healthy young group (p<0.001), and in the dysphagic elderly group than in the healthy elderly group (p<0.001). The sensitivity and specificity of SCT were 73.8% and 72.5% for detecting aspiration in the dysphagic patients, and 87.1% and 66.7% for detecting silent aspiration in the aspirated patients.ConclusionCough latency measured with the SCT reflects the impairment of cough reflex in healthy elderly and dysphasic subjects. The results of this study show that the SCT test can be a valuable method of screening aspiration with or without cough in dysphasic patients.

show abstract

Section: Discussionmentioning

confidence: 99%

Usefulness of the Simplified Cough Test in Evaluating Cough Reflex Sensitivity as a Screening Test for Silent Aspiration

et al. 2014

View full text Add to dashboard Cite

show abstract

“… 57 However, most studies support that COPD patients have a higher cough sensitivity compared with healthy subjects. 57 , 58 A study by Cho et al 12 suggested that the higher cough sensitivity for capsaicin is associated with chronic cough in COPD patients, which is an inspiration for subsequent studies. As for asthma, the cough sensitivity of patients with stable asthma do not differ from healthy subjects, while the cough sensitivity of cough variant asthma is significantly increased.…”

Section: Recent Progresses In Clinical Applications Of the Cough Chal...mentioning

confidence: 99%

Similarities and differences between the cough suppression test and the cough challenge test

Zhao

Bai

Wen

et al. 2023

Ther Adv Respir Dis

View full text Add to dashboard Cite

In recent years, a new test method namely the cough suppression test has been proposed to measure cough suppression in patients with chronic cough. The cough suppression test is a modified test based on capsaicin tussive challenge. There are similarities and differences between it and the more established cough challenge test in detection method, purpose and clinical significance. In this article, we will introduce and compare the concepts, application and methodology of the cough suppression test and the cough challenge test, summarize this research progress and problems of the two methods, and predict the possible role of both in the further study of chronic cough.

show abstract

“…Smith et al . reported that nocturnal cough frequency was associated with worse cough-specific health status (r=0.50) in COPD, thus suggesting that cough is likely a determinant of health status in COPD ( 71 ).…”

Section: Copdmentioning

confidence: 99%

Cough in chronic lung disease: a state of the art review

Hirons,

Rhatigan,

Kesavan

et al. 2023

J Thorac Dis

View full text Add to dashboard Cite

Chronic cough (CC; ≥8 weeks in duration) is a common and burdensome feature of respiratory diseases. The understanding of cough has progressed significantly in recent years, albeit largely in refractory (unexplained) chronic cough (RCC) in the absence of other respiratory conditions. The prevalence of CC in respiratory diseases is poorly described, but estimates have been reported: asthma (8–58%), chronic obstructive pulmonary disease (COPD; 10–74%), bronchiectasis (82–98%), interstitial lung disease (ILD; 50–89%) and sarcoidosis (3–64%). CC in respiratory conditions generally predicts impaired health status and more severe disease. It is associated with increased symptom burden and disease severity in asthma, COPD, bronchiectasis and ILD, higher exacerbation frequency in asthma and bronchiectasis, and increased mortality and lung transplantation in idiopathic pulmonary fibrosis (IPF). Physiologically, heightened cough reflex sensitivity (CRS) has been reported and postulated to be mechanistic in isolated RCC. Cough reflex hypersensitivity (CRH) has also been reported in asthma, COPD, bronchiectasis, ILD and sarcoidosis. Unlike recent advances in isolated RCC, there are limited studies and understanding of central cough neuropathways in other respiratory conditions. Of note, dysfunctional central voluntary cough suppression neuropathways and physiology were observed in isolation in RCC; cough suppression is preserved in COPD. Understanding in the mechanism of RCC cannot be simply extrapolated to other respiratory conditions. The restricted understanding of cough mechanisms in these conditions has limited cough-specific therapeutic options in this context. There is currently an unmet need to expand our understanding of cough in chronic respiratory conditions, both in order to improve the quality of life of patients, and to improve knowledge of cough in general. This review aims to describe the prevalence, impact, pathophysiology and management of CC in asthma, COPD, bronchiectasis, ILD and sarcoidosis.

show abstract

Cough in COPD

Cited by 34 publications

References 18 publications

Usefulness of the Simplified Cough Test in Evaluating Cough Reflex Sensitivity as a Screening Test for Silent Aspiration

Usefulness of the Simplified Cough Test in Evaluating Cough Reflex Sensitivity as a Screening Test for Silent Aspiration

Similarities and differences between the cough suppression test and the cough challenge test

Cough in chronic lung disease: a state of the art review

Contact Info

Product

Resources

About