Coulometric determination of the water content of dimethylacetamide

Amperometric, bipotentiometric, and coulometric titration

“…The biamperometric and bipotentiometric Karl Fischer endpoint techniques have been examined and found to give comparable results (221). Bipotentiometric indication was used in the coulometric determination of H20 in dimethylacetamide (39).…”

Titrations in nonaqueous solvents

“…Up to 10 determinations can be made in one portion of analyte. Other reports include coulometric generation of Karl Fischer reagent for the determination of moisture in gases (210), in dimethylacetamide (52), and in several organic solvents (211). The rate of reaction between water and Karl Fischer reagent is said to be 100 times faster when 40 vol% formamide in pyridine is substituted for the conventional methanolic reagent (55).…”