Coumarins of the roots ofSeseli grandivittatum

Turabelidze, D. G.; Кемертелидзе, Э. П.

doi:10.1007/bf00564817

Cited by 1 publication

(3 citation statements)

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“…[α] D 27 = À 78.4 (ethanol), [24] [α] D = À 74 (ethanol) [61] and [α] D = À 46.5. [45] In addition, (+)-praeruptorin B [(+)-anomalin] with [α] D = + 38.9 (CHCl 3 ) was determined in Peucedanum praeruptorum Dunn.…”

Section: Physicochemical-structural Propertiesmentioning

confidence: 99%

“…Isolation and purification procedures of anomalin are also summarized in Table 1. As can be seen, anomalin was obtained from either aerial part and roots of the plant by extraction with petroleum ether, [36,56,57,60,68] hexane, [59,62,64–67] diethyl ether, [70] chloroform, [51] methanol, [24,26,38,39,45–50,52–54,61,69,70] ethanol, [40,44,55,73,74] acetone, [41,57–59] etc. at room temperature or by reflux.…”

Section: Sources and Isolationmentioning

confidence: 99%

“…Anomalin (praeruptorin B) is usually present as a mixture of enantiomers in the plants in different proportions and therefore, leads to different values of the optical rotation as it is reported in the literature: [α] D 27 =−78.4 (ethanol), [24] [α] D =−74 (ethanol) [61] and [α] D =−46.5 [45] . In addition, (+)‐praeruptorin B [(+)‐anomalin] with [α] D =+38.9 (CHCl 3 ) was determined in Peucedanum praeruptorum Dunn [49] .…”

Section: Physicochemical‐structural Propertiesmentioning

confidence: 99%

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A Review on Anomalin: A Natural Bioactive Pyranocoumarin from the Past to the Future

Önder

Трендафилова

2022

Chemistry & Biodiversity

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Anomalin is a seselin-type pyranocoumarin isolated for the first time from Angelica anomala Avé-Lal, but is also found in several other plant species, especially in Apiaceae. This lipophilic molecule possesses pharmacologically beneficial activities for human health. The major scientific databases Scopus, Web of Science, Google Scholar, and PubMed up to the end of 2021 and the combining terms anomalin, praeruptorin, isolation, structure elucidation, and biological activity were used in the research of this review. This review focuses on the sources, structural properties, and biological functions of anomalin and provides future trends in the investigation of anomalin, particularly in therapies for many common diseases such as anti-inflammatory and neurodegenerative illnesses. As a potential bioactive molecule, prospective studies on anomalin should be done through supported clinical trials. At the end, this review confirms the significant pharmacological potential of anomalin.

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Section: Physicochemical-structural Propertiesmentioning

confidence: 99%