Coumarins

Natural compounds, fraxin and chemicals structurally related to fraxin protect cells from oxidative stress

“…To date, at least 1,300 coumarins have been identified, principally as secondary metabolites in green plants but also in fungi and bacteria (Murray, 1989;Hoult and Paya, 1996). The prototypical compound is coumarin itself (also known as 1,2-benzopyrone or less commonly, as o-hydroxycinnamic acid-8-lactone), and it has been well studied.…”

Determination of excited singlet-state dipole moments of hydroxy and methoxy coumarins using solvatochromic method

“…They also alter the dipole moment in ground and excited states. This helps in understanding the behavior of these compounds in ground and excited states [15][16][17].…”

Synthesis, Physico-Chemical investigations of Co(II), Ni(II) and Cu(II) complexes and their in vitro microbial, cytotoxic, DNA cleavage studies

“…They are also a very interesting class of compounds because of their wide application as antimicrobial 14 , anti-inflammatory 15 , antidegenerative 16 , and anti-human immunodeficiency virus (HIV) 17 activities. In addition to the thiazole derivatives, coumarins and their derivatives display not only important structural variety but also significant biological [18][19][20][21][22] and pharmacological 23,24 properties. Many of these compounds possess antibacterial 23 , antifungal 24 , and insecticidal 21 activities, and also the hydroxycoumarins are typical phenolic compounds and therefore act as potent metal chelators and free radical scavengers.…”