A d-dimensional polycube of size n is a connected set of n cubes in d dimensions, where connectivity is through (d − 1)-dimensional faces. Enumeration of polycubes, and, in particular, specific types of polycubes, as well as computing the asymptotic growth rate of polycubes, is a popular problem in combinatorics and discrete geometry. This is also an important tool in statistical physics for computations and analysis of percolation processes and collapse of branched polymers. A polycube is said to be proper in d dimensions if the convex hull of the centers of its cubes is d-dimensional. In this paper we prove that the number of polycubes of size n that are proper in n − 3 dimensions is 2 n−6 n n−7 (n − 3)(12n 5 − 104n 4 + 360n 3 − 679n 2 + 1122n − 1560)/3.