2022
DOI: 10.1016/j.ijid.2021.11.004
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Country differences in transmissibility, age distribution and case-fatality of SARS-CoV-2: a global ecological analysis

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Cited by 12 publications
(13 citation statements)
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“…However, this may be less to do with response efforts and more to do with population characteristics (e.g. age, outdoor social mixing) [39] and/or inadequate surveillance. Anecdotal reports as well as recent studies suggest that the impact in terms of mortality was indeed much higher than reported [40,41].…”
Section: Discussionmentioning
confidence: 99%
“…However, this may be less to do with response efforts and more to do with population characteristics (e.g. age, outdoor social mixing) [39] and/or inadequate surveillance. Anecdotal reports as well as recent studies suggest that the impact in terms of mortality was indeed much higher than reported [40,41].…”
Section: Discussionmentioning
confidence: 99%
“…The estimated prevalence (C19-Prev) is defined as the number of confirmed COVID-19 cases per 1 million population, while the crude mortality rate (CMR) is defined as the number of confirmed deaths due to COVID-19 per 1 million population, and the case-fatality ratio (CFR) is the ratio of deaths to total cases of COVID-19, expressed as a percentage. Though these measures have certain inherent limitations due to variations in testing, reporting and death certification practices, they have been widely used to quantify the severity of the pandemic at a cross-national level (Favas et al, 2022 ). Information on these variables was obtained from the Johns Hopkins University's global COVID-19 data aggregator.…”
Section: Methodsmentioning
confidence: 99%
“…Notwithstanding these challenges, sub-Saharan Africa (SSA) appears to be minimally impacted by the pandemic, with fewer confirmed and reported COVID-19 cases and mortalities than elsewhere. The demographic distribution (a key epidemiological indicator of disease transmission), low case detection rate due to insufficient testing capacity, epidemiological disparities, and timely implementation of NPIs best explain the variations in the burden of COVID-19 observed across different settings ( Evans et al, 2020 ; Favas et al, 2022 ; Ram & Schaposnik, 2021 ; Taboe et al, 2020 ). The young population age-structure in Africa with a median age of 19 years is significant in limiting morbidity and mortality associated with the disease ( Favas et al, 2022 ; Ram & Schaposnik, 2021 ).…”
Section: Introductionmentioning
confidence: 99%
“…The demographic distribution (a key epidemiological indicator of disease transmission), low case detection rate due to insufficient testing capacity, epidemiological disparities, and timely implementation of NPIs best explain the variations in the burden of COVID-19 observed across different settings ( Evans et al, 2020 ; Favas et al, 2022 ; Ram & Schaposnik, 2021 ; Taboe et al, 2020 ). The young population age-structure in Africa with a median age of 19 years is significant in limiting morbidity and mortality associated with the disease ( Favas et al, 2022 ; Ram & Schaposnik, 2021 ). Evidence from various studies has associated a greater risk of disease severity and mortality with older and immunocompromised individuals ( Davies et al, 2020 ; Sadarangani et al, 2021 ; Simeni Njonnou et al, 2021 ).…”
Section: Introductionmentioning
confidence: 99%