Coupling of acyl chlorides with triarylbismuths catalyzed by palladium bipyridyl complex anchored on nanosized MCM-41: A recyclable and atom-efficient catalytic process for the synthesis of diaryl and alkyl aryl ketones

Sonogashira Reaction of Aryl and Heteroaryl Halides with Terminal Alkynes Catalyzed by a Highly Efficient and Recyclable Nanosized MCM-41 Anchored Palladium Bipyridyl Complex

“…Several studies have successfully determined the amount of metal leaching using a hot-filtration technique, and this method was therefore used in this study to examine the activity of the catalyst with regards to metal leaching [ 45 , 46 , 47 , 48 , 56 , 57 , 58 ]. A reaction mixture of 1a with 2a in the above-described catalytic system was stirred at 50 °C for 30 min, resulting in a GC yield of 32%.…”

“…Although most known heterogeneous catalysts have been demonstrated to be able to be recycled for use in further runs, the use of catalytic amounts of 0.2–5 mol% of Pd for the Sonagashira reaction is still too high for a single batch reaction when compared with homogeneous catalysts [ 49 , 50 , 51 , 52 , 53 , 54 ]. We have recently prepared a nanosized MCM-41 grafted palladium bipyridyl complex, NS-MCM-41-Pd ( Figure 1 ), as a highly efficient and recyclable catalyst for the Mizoroki-Heck reaction [ 55 ], Kumada-Tamao-Corriu reaction [ 56 ], ketone formation [ 57 ], and ynone formation [ 58 ], which require a very low catalyst loading for a single batch reaction.…”